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  • 11. Photosynthesis: Capturing Sunlight
    2026/09/11

    Daniel Arnon gets isolated chloroplasts to make ATP out of light. Melvin Calvin, Andrew Benson and James Bassham feed radioactive carbon dioxide to algae and trace, one compound at a time, the path carbon takes into sugar. Bessel Kok counts the flashes of light it takes to release a single molecule of oxygen. Johann Deisenhofer and Hartmut Michel crystallize a membrane protein everyone had said could not be crystallized, and win the first atomic picture of a photosynthetic reaction center.


    Season Two of We Are Biochemistry is the people behind the pathways, drawn from The Molecule Hunters, the book written by more than five hundred University of Virginia students.


    Pairs with Biochemistrypedia Chapter 22, Photosynthesis: The Light Reactions - biochemistrypedia.com


    The full book, its sources, and the individual student credits are free at deppmannlab.com, where the corrections form also takes audiobook pronunciation fixes.


    Narrated by a digital voice.

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    18 分
  • 10. Bioenergetics: Proton Gradients and ATP
    2026/09/09

    Albert Lehninger pins oxidative phosphorylation to the mitochondrion. Peter Mitchell proposes that a cell's energy is stored as a difference in protons across a membrane, is told for the better part of two decades that this is theology rather than biochemistry, restores a manor house with his own hands while he waits, and is finally proved right. Paul Boyer works out that the enzyme making ATP does so by turning, and John Walker's crystals show the turning parts. Nathan Kaplan and Philip Handler build the field around them.


    Season Two of We Are Biochemistry is the people behind the pathways, drawn from The Molecule Hunters, the book written by more than five hundred University of Virginia students.


    Pairs with Biochemistrypedia Chapter 21, The Proton-Motive Force and ATP Synthase - biochemistrypedia.com


    The full book, its sources, and the individual student credits are free at deppmannlab.com, where the corrections form also takes audiobook pronunciation fixes.


    Narrated by a digital voice.

    続きを読む 一部表示
    26 分
  • 9. The Krebs Cycle, Respiration, and the Sugar Economy (Part 3 of 3)
    2026/09/07

    Carl and Gerty Cori take the body's vaguest mystery, what becomes of sugar, and reduce it to a cycle running between muscle and liver - work she did as an unpaid research associate at a fraction of his salary, until they shared the Nobel Prize. Sidney Colowick comes up through their laboratory and helps turn enzymology into a discipline with standard methods. Luis Federico Leloir finds the sugar nucleotides, and with them how a body builds glycogen rather than merely spending it.


    Season Two of We Are Biochemistry is the people behind the pathways, drawn from The Molecule Hunters, the book written by more than five hundred University of Virginia students.


    Pairs with Biochemistrypedia Chapter 19, The Citric Acid Cycle: Harvesting Electrons - biochemistrypedia.com


    The full book, its sources, and the individual student credits are free at deppmannlab.com, where the corrections form also takes audiobook pronunciation fixes.


    Narrated by a digital voice.

    続きを読む 一部表示
    22 分
  • 8. The Krebs Cycle, Respiration, and the Sugar Economy (Part 2 of 3)
    2026/09/05

    Hans Krebs maps the wheel at the centre of metabolism, working as a refugee from Nazi Germany in a borrowed laboratory, and publishes it in an obscure journal after Nature turns it away. Fritz Lipmann finds coenzyme A and gives the high-energy phosphate bond its meaning. David Keilin picks up a hand spectroscope, looks at a living insect, sees bands appear and disappear as it breathes, and recognises the respiratory chain.


    Season Two of We Are Biochemistry is the people behind the pathways, drawn from The Molecule Hunters, the book written by more than five hundred University of Virginia students.


    Pairs with Biochemistrypedia Chapter 19, The Citric Acid Cycle: Harvesting Electrons - biochemistrypedia.com


    The full book, its sources, and the individual student credits are free at deppmannlab.com, where the corrections form also takes audiobook pronunciation fixes.


    Narrated by a digital voice.

    続きを読む 一部表示
    21 分
  • 7. The Krebs Cycle, Respiration, and the Sugar Economy (Part 1 of 3)
    2026/09/03

    Albert Szent-Gyorgyi pulls a stubbornly unidentifiable reducing agent out of adrenal glands, oranges and finally Hungarian paprika, names it ascorbic acid, and takes a Nobel Prize for vitamin C and the chemistry of cellular combustion. Otto Warburg builds the instruments that let anyone measure what a cell does with oxygen, works out the respiratory enzyme, and carries on through Nazi Germany under circumstances that killed almost everyone like him.


    Season Two of We Are Biochemistry is the people behind the pathways, drawn from The Molecule Hunters, the book written by more than five hundred University of Virginia students.


    Pairs with Biochemistrypedia Chapter 19, The Citric Acid Cycle: Harvesting Electrons - biochemistrypedia.com


    The full book, its sources, and the individual student credits are free at deppmannlab.com, where the corrections form also takes audiobook pronunciation fixes.


    Narrated by a digital voice.

    続きを読む 一部表示
    12 分
  • 6. Following the Carbon: Tracers and Metabolic Maps
    2026/09/01

    Heinrich Wieland argues that biological oxidation is a matter of taking hydrogen away rather than adding oxygen, and spends years arguing it with Otto Warburg. Rudolf Schoenheimer feeds animals molecules labelled with heavy isotopes and discovers that the body is not a stable structure being topped up but a thing in constant turnover, its own material continually replaced. Yellapragada SubbaRow works out phosphocreatine and ATP, and goes on to methotrexate. Herman Kalckar ties phosphorylation to respiration.


    Season Two of We Are Biochemistry is the people behind the pathways, drawn from The Molecule Hunters, the book written by more than five hundred University of Virginia students.


    Pairs with Biochemistrypedia Chapter 15, Metabolism: Basic Concepts and Design - biochemistrypedia.com


    The full book, its sources, and the individual student credits are free at deppmannlab.com, where the corrections form also takes audiobook pronunciation fixes.


    Narrated by a digital voice.

    続きを読む 一部表示
    23 分
  • 5. Vitamin Chemistry: Isolating and Synthesizing Life's Catalysts
    2026/08/30

    Identifying a deficiency was the easy half of the problem. Drawing the molecule, and then making it by the ton, was the hard one. Paul Karrer's laboratory in Zurich looks less like a chemistry institute than a flower market, crates of crocuses and carrots waiting to be boiled down, and out of the colour he reads the first structure ever established for a vitamin. Adolf Windaus cracks a sterol ring open with ultraviolet light and gets vitamin D. Tadeus Reichstein hands the one step organic chemistry could not manage to a bacterium, and scurvy becomes an industrial fermentation. Roger Williams isolates pantothenic acid, the vitamin that turns out to be everywhere.


    Season Two of We Are Biochemistry is the people behind the pathways, drawn from The Molecule Hunters, the book written by more than five hundred University of Virginia students.


    Pairs with Biochemistrypedia Chapter 15, Metabolism: Basic Concepts and Design - biochemistrypedia.com


    The full book, its sources, and the individual student credits are free at deppmannlab.com, where the corrections form also takes audiobook pronunciation fixes.


    Narrated by a digital voice.

    続きを読む 一部表示
    12 分
  • 4. The Vitamin Hunters: Invisible Essentials
    2026/08/28

    Christiaan Eijkman notices in Java that chickens fed polished rice cannot walk, and that the husks cure them. Frederick Gowland Hopkins proves that animals fed pure protein, fat, carbohydrate, salt and water still fail to grow, so something else must be required in traces. Elmer McCollum sorts the fat-soluble factors from the water-soluble. Lucy Wills traces a fatal anaemia among mill workers in Bombay to something in yeast extract. Henrik Dam finds the factor that lets blood clot, and Conrad Elvehjem cures black tongue with nicotinic acid.


    Season Two of We Are Biochemistry is the people behind the pathways, drawn from The Molecule Hunters, the book written by more than five hundred University of Virginia students.


    Pairs with Biochemistrypedia Chapter 15, Metabolism: Basic Concepts and Design - biochemistrypedia.com


    The full book, its sources, and the individual student credits are free at deppmannlab.com, where the corrections form also takes audiobook pronunciation fixes.


    Narrated by a digital voice.

    続きを読む 一部表示
    23 分