In this insightful radio broadcast, clinical nutritionist Corinne Furnari and pharmacist Carol Petersen take a deep dive into the often-misunderstood condition of histamine intolerance—frequently mistaken for seasonal or environmental allergies. They explain that histamine is not simply a substance involved in allergic reactions, but a powerful compound that functions both as an inflammatory mediator and an important neurotransmitter. When histamine levels rise beyond the body’s ability to break them down, symptoms can become widespread and unpredictable, ranging from migraines and heart palpitations to digestive distress, anxiety, skin rashes, and insomnia.

A key focus of the discussion is the intricate relationship between hormones—particularly progesterone—and histamine regulation. The hosts describe how progesterone helps stabilize mast cells (the cells responsible for releasing histamine) and supports the activity of enzymes that metabolize and clear excess histamine. When progesterone levels are low, as can occur during perimenopause, menopause, or periods of hormonal imbalance, histamine symptoms often intensify. This hormonal connection helps explain why many women experience cyclical flares that are frequently dismissed or misdiagnosed.

Corinne and Carol also emphasize that conventional allergy testing often fails to identify histamine intolerance, since the issue is not always an immune reaction but rather an impaired ability to degrade histamine efficiently. Instead, they suggest practical strategies such as a structured elimination diet to identify triggers, along with targeted nutrient support. Key nutrients discussed include vitamin C, vitamin B6, and zinc—each playing a role in supporting histamine breakdown and immune balance.

Finally, the hosts underscore the foundational role of gut health and methylation pathways in long-term recovery. A balanced gut microbiome helps regulate histamine production, while proper methylation supports detoxification and metabolic processing. By addressing hormonal balance, digestive health, and nutritional deficiencies together, they present a comprehensive framework for reducing symptoms and restoring resilience in those struggling with histamine overload.

⁠⁠https://corinnehealth.com/⁠⁠⁠⁠⁠

⁠⁠⁠⁠⁠https://thewellnessbydesignproject.com/

The Liver: Your Body’s Metabolic Powerhouse

In this radio broadcast, nutritionist Corinne Furnari and pharmacist Carol Petersen explore the liver’s role as the body’s primary biochemical factory. They explain how the liver regulates blood volume, stabilizes blood sugar, filters toxins, produces bile, and processes nutrients, emphasizing that nearly every metabolic function depends on its health. Despite its heavy workload, the liver is uniquely resilient and capable of regeneration when properly supported.

The hosts caution that chronic high insulin levels and fatty liver disease—especially non-alcoholic fatty liver disease—can progressively impair liver function. Modern diets high in sugar, refined carbohydrates, and frequent snacking place constant stress on the liver, limiting its ability to complete detoxification and repair cycles. Over time, this metabolic overload can contribute to insulin resistance, inflammation, and widespread systemic health issues.

To reduce this burden, Furnari and Petersen highlight the benefits of intermittent fasting and a whole-foods diet. Allowing longer intervals between meals gives the liver time to rest, repair, and shift its energy toward detoxification rather than constant glucose regulation. They also discuss supportive natural approaches, including milk thistle, targeted amino acids, and traditional practices such as coffee enemas, noting that these methods should be used thoughtfully and tailored to individual needs.

Listener questions expand the discussion to related concerns such as acid reflux and urinary tract infections. In response, the hosts suggest alternatives like DGL licorice and zinc to support digestive and mucosal health without suppressing stomach acid. Throughout the broadcast, they emphasize the liver’s remarkable capacity to heal when metabolic stress is reduced and consistent, nutrition-focused lifestyle changes are applied.

⁠⁠https://corinnehealth.com/⁠⁠⁠⁠

⁠⁠⁠⁠https://thewellnessbydesignproject.com/

In this episode of Take Charge of Your Health, hosts Corinne Furnari and Carol Petersen explore the growing crisis of fatty liver disease, describing it as a largely unnoticed epidemic now affecting both adults and children. They differentiate between alcohol-related liver damage and non-alcoholic fatty liver disease (NAFLD), emphasizing that NAFLD is driven primarily by modern diets high in ultra-processed foods and high-fructose corn syrup.

The hosts explain that although the liver has a remarkable capacity to regenerate, it can become overwhelmed by chronic toxic exposure, gut dysfunction, and the frequent use of common medications such as acetaminophen.

To support liver recovery, they highlight practical lifestyle strategies including optimizing vitamin C and magnesium intake, improving digestion with supports like hydrochloric acid, and reducing exposure to environmental toxins such as glyphosate. Stay tuned for another episode on this subject.

⁠https://corinnehealth.com/⁠⁠⁠

⁠⁠⁠https://thewellnessbydesignproject.com/