Two women. An office filled with secrets. One terrible crime that can't be taken back. Dawn Schiff is strange. At least, everyone thinks so at Vixed, the nutritional supplement company where Dawn works as an accountant. She never says the right thing. She has no friends. And she is always at her desk at precisely 8:45 a.m.

Tokyo resident Keiko Furukara has never fit in - neither in her family, nor in school - but when at the age of 18 she begins working at the Hiiromachi branch of national convenience store chain Smile Mart, she realizes instantly that she has found her purpose in life. Delighted to be able to exist in a place where the rules of social interaction are crystal clear (many are laid out line-by-line in the store's manual), Keiko does her best to copy the dress, mannerisms, and mode of speech of her colleagues, playing the part of a "normal" person excellently, more or less.

As a child, Natsuki doesn’t fit into her family. Her parents favor her sister, and her best friend is a plush toy hedgehog named Piyyut who has explained to her that he has come from the planet Popinpobopia on a special quest to help her save the Earth.

An aspiring writer moves into a new apartment and discovers that her landlady has murdered her husband. Elsewhere, an accomplished surgeon is approached by a cabaret singer, whose beautiful appearance belies the grotesque condition of her heart. And while the surgeon's jealous lover vows to kill him, a violent envy also stirs in the soul of a lonely craftsman. Desire meets with impulse and erupts, attracting the attention of the surgeon's neighbor - who is drawn to a decaying residence that is now home to instruments of human torture.

Akira Kido is a divorce attorney whose own marriage is in danger of being destroyed by emotional disconnect. With a midlife crisis looming, Kido's life is upended by the reemergence of a former client, Rié Takemoto. She wants Kido to investigate a dead man - her recently deceased husband, Daisuké. Upon his death she discovered that he’d been living a lie. His name, his past, his entire identity belonged to someone else, a total stranger.