Do you know how aptamers are revolutionizing brain research! How can you accurately distinguish between dopamine, adrenaline, and noradrenaline in a biological fluid filled with countless other molecules?

Join us as we explore the exciting world of aptamers with Prof. Nako Nakatsuka from the Laboratory of Chemical Nanotechnology (CHEMINA) at Neuro_X_EPFL. Nako’s pioneering research is reshaping how we detect chemicals in the brain and diagnose neurodegenerative diseases, including Parkinson’s and Alzheimer’s disease.

In this episode, we cover:

• The fundamentals of aptamers and their design
• Techniques for neurotransmitter detection
• The role of aptamers in brain disease
• Future applications/research directions, and more!

#Aptamers #Biosensors #Neurotransmitters #ParkinsonsDisease #MedicalResearch #EPFL #SciencePodcast #Innovation #Neuroscience #Research


Images provided by Prof. Nakatsuka and from the following references:

https://www.mdpi.com/2227-9040/11/10/523

https://www.sciencedirect.com/science/article/abs/pii/S0300908420302637

https://mhanational.org/neurons-how-brain-communicates

https://www.sciencedirect.com/science/article/abs/pii/S1226086X22005639

https://www.frontiersin.org/journals/aging-neuroscience/articles/10.3389/fnagi.2015.00136/full

https://www.wzbio.com/aavZt.php?pid=1&id=4&cid=2&tid=2

https://www.science.org/doi/epdf/10.1126/science.abf4588

https://www.semanticscholar.org/paper/Advances-in-Scanning-Ion-Conductance-Microscopy%3A-Li-Li/3caf1595c9144033fbc00d187d7bf36f8ee7feb1

https://www.creative-biostructure.com/application-of-circular-dichroism-spectroscopy-in-nucleic-acid-research.html

https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2018.00158/full

https://www.jasco-global.com/solutions/monitoring-of-protein-behavior-by-using-fret/