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  • The Dark Proteome

    The Dark Proteome
    2025/02/04
    Even though it was completed a quarter century ago, geneticists still struggle to estimate the number of genes in the human genome. They went from ‘hundreds of thousands’ to “22 thousand”, then more recently to “about 19,500”. The number, however, has just exploded. Tens of thousands of new genes with important functions were discovered hiding in the ‘junk DNA’. Dr Rob explains what these new findings mean to the creation-evolution debate. Links and notes: Carter 2025 The dark proteome https://creation.com/dark-proteome Carter 2024 The incredible shrinking human genome, https://biblicalgenetics.com/shrinking-genome/ Amaral et al. 2024 The status of the human gene catalogue, Nature 622(7981):41–47; https://pubmed.ncbi.nlm.nih.gov/37794265/ Prensner et al. 2024 What can Ribo-seq and proteomics tell us about the non-canonical proteome? https://www.biorxiv.org/content/10.1101/2023.05.16.541049v1 Pennisi 2024 ‘Dark proteome’ survey reveals thousands of new human genes, Science 386(6725):951–952; https://pubmed.ncbi.nlm.nih.gov/39607933/ Podcast: https://biblicalgenetics.com/contra-creation-myths Carter et al. 2004 Cloning of anthozoan fluorescent protein genes, Comparative Biochemistry and Physiology, Part C 138:259–270; https://pubmed.ncbi.nlm.nih.gov/15533784 Matz et al. 1999 Fluorescent proteins from nonbioluminescent Anthozoa species, Nature Biotechnology 17(10):969–973; https://pubmed.ncbi.nlm.nih.gov/10504696/
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    22 分
  • Dedicated anti-creationist makes huge blunder

    Dedicated anti-creationist makes huge blunder
    2025/01/28
    In a recent presentation on human-chimp similarities to LOGOS Research Associates, I made the (correct) claim that most new mutations are lost. An opponent attempted to make hay of this, claiming it disproves the 'creationist' calculations of the time to Y Chromosome Adam and Mitochondrial Eve. What he failed to understand, however, is that the Y and mt chromosomes are haploid and behave very differently to the rest of the genome. In fact, mutations occur in them in a ratchet-like manner and no degree of natural selection can change that. Do you want a lesson in population genetics? Tune in! Notes and links: My presentation to LOGOS Research Associates: "Chimp and Human (Dis)similarities by Dr. Robert Carter" Dan's attempt at a rebuttal: "Professional Creationist Makes Huge Admission" by Creation Myths An older video where I answer the same claims (Creation Myths ignores other people!): Genealogy vs Phylogeny: The War Continues Rupe and Sanford (2013) Using Numerical Simulation to Better Understand Fixation Rates, and Establishment of a New Principle: Haldane’s Ratchet Carter (2023) Genealogical vs Phylogenetic Mutation Rates: Answering a Challenge Fixation (population genetics) on Wikipedia A shrinking date for Eve Natural Selection in Paradise The 'two circles' illustration
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    1 時間 29 分
  • Your favorite cheese might be facing extinction

    Your favorite cheese might be facing extinction
    2025/01/21
    In a recent Creation magazine article, I talked about an interesting new case study done on one of the world's most favorite cheeses, Brie, and its relatives Camembert and Roquefort. A long time ago, cheesemakers unknowingly selected non-sexually reproducing fungal lines for these cheeses. Now, many decades later, mutations have built up in this lines to the point where they are starting to have trouble reproducing. Rescue efforts are underway, but in the meantime this gives us an object lesson about the impossibility of evolution, specifically the survival of the first organisms, which would not have been able to go through sexual recombination. Links: The Creation magazine paper: creation.com/cheese-verge-of-extinction Signup for Creation magazine here: creation.com/en-us/creation-magazine The original research: Harmi, M., French cheese under threat, news.cnrs.fr, 16 Jan 2024. Additional info on Muller's ratchet: dl0.creation.com/articles/p145/c14588/j29_2_70-77.pdf About Dr. Robert Carter: creation.com/dr-robert-carter-cv
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    5 分
  • Mendel’s Law of Exponential Trait Combination

    Mendel’s Law of Exponential Trait Combination
    2024/11/26
    Gregor Mendel was the father of modern genetics. He wrote his most important papers on the topic just a few years after Darwin published the Origin of Species. What people don't realize is that Mendel's papers did not only describe how traits are passed down. He also explained how his ideas of genetics lead directly to an explanation of the origin of species. Was Mendel directly and purposefully contradicting Darwin? Links and notes: Crompton et al. 2024 Mendelian speciation, part 1—what is the abundant source of significant biodiversity, J Creation 37(3):110–120, 2023. Crompton et al. 2024 Mendelian speciation, part 2—latent genetic information, J Creation 38(1):77–86, 2024. Crompton et al. 2024 Mendelian speciation, part 3—fixation and reproductive isolation, J Creation 382):97–104, 2024. Crompton et al. 2024 Mendelian speciation, part 4—adaptive radiations and cis-evolution, J Creation 38(2):105–112, 2024. Gregor Mendel on Wikipedia "They believe in bigger miracles than I do" on YouTube.com Species were designed to change on BiblicalGenetics.com Species were Designed to Change on Creation.com Arguments we think a creationist should not use on creation.com Wort und Wissen
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    14 分
  • Seabird shennanigans

    Seabird shennanigans
    2024/11/12
    Dr Carter spent some time recently in New Zealand. While there, he stopped by a giant colony of gannets. These sea birds number in the millions but they create a bit of a taxonomic mystery. Are three living species of gannets and the eight living species of booby one 'created kind'? What about the cormorants? Should they also be included? Baraminology has not revealed the limits of the created kinds, so we have much work still to do. Notes and links: Species were designed to change, part 1 God Deliberately Engineered Life to Change, but How Much Change is Allowed? Biblical Biology 101 (my new book!)
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    10 分
  • Placing Noah’s sons on the Y chromosome tree

    Placing Noah’s sons on the Y chromosome tree
    2024/10/29
    It is only natural for people to want to compare the Table of Nations (Genesis 10) to geography, linguistics, ancient history, and/or patterns in human DNA. The solution, however, is harder than most people think. Here, I list multiple reasons why it might actually be impossible to know where Shem, Ham, and Japheth belong even though Genesis is true. Notes and links: Carter, R., Can we place the sons of Noah on the Y chromosome tree? The solution is harder than most people think, 29 Oct 2024. Distribution map of haplogroup R1b in the Old World”, eupedia.com/europe/Haplogroup_R1b_Y-DNA.shtml. Carter, R.W., Patriarchal drive in the early post-Flood population, J. Creation 33(1):110–118, 2019; creation.com/patriarchal-drive. Additional references can be found in the main article.
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    26 分
  • DNA from the last woolly mammoths supports the Bible

    DNA from the last woolly mammoths supports the Bible
    2024/09/18
    The woolly mammoth is strongly associated with the Ice Age, but they survived until surprisingly recent times in the far north. Recently, the genomes of multiple mammoths from the last surviving population on Wrangel Island were sequenced. The scientists concluded the population was founded by 8 or fewer individuals and only 1 mitochondrial lineage was among them. They also estimated that the population grew to a few hundred before finally going extinct. This, it turns out, is a wonderful natural laboratory for biblical events. Consider that there were only 8 people on the Ark. How much genetic diversity would we expect to lose? Is that population too small to prevent so much inbreeding that humans would have gone into mutational meltdown? Etc. Etc. Carter, R., DNA from the last woolly mammoths: surprising results support the Flood account, creation.com. Dehasque M et al., Temporal dynamics of woolly mammoth genome extension prior to extinction, Cell 187(14):3531–3540.e13, 2024. Carter R, Biblical bottlenecks are not bad, biblicalgenetics.com, 27 May 2020. Carter R, Evolutionary bottlenecks are disastrous, biblicalgenetics.com, 2 Jun 2020. Carter R, Did we evolve from 10,000 people in Africa? biblicalgenetics.com, 19 Jul 2022. Carter R, Evolutionists predict super bottleneck (it would have killed us), biblicalgenetics.com, 9 Nov 2023. Carter R and Powell M, The genetic effects of the population bottleneck associated with the Genesis Flood, Journal of Creation 30(2):102–111, 2018. Carter R, Effective population sizes and loss of diversity during the Flood bottleneck, Journal of Creation 32(2):124–127, 2018. Carter R, Mutations and why you shouldn't marry your cousin, creation.com, 12 Aug 2017. Carter R, How carbon dating works, creation.com, 12 Apr 2022.
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    20 分
  • Natural selection has little power in the real world

    Natural selection has little power in the real world
    2024/09/10
    Mike Lynch and colleagues published a paper that is devastating to thousands of past studies on natural selection. By sequencing DNA from multiple natural populations over several years, they showed that the net effect of natural selection is "zero" for most genetic variants. They caution that selection pressures in the natural world fluctuate. This cause the chromosomal targets of selection to shift over time, etc., meaning that many thousands of scientific studies that found evidence for natural selection are probably wrong. This paper is a gold mine of quotes, so Dr Rob quotes it extensively. Links: Carter, R., Natural selection in the real world is mostly ineffective, creation.com. Daphnia: wikipedia.org/wiki/Daphnia Lynch et al., The genome-wide signature of short-term temporal selection, PNAS 121(28):e2307107121, 2024; pubmed.ncbi.nlm.nih.gov/38959040 Darwin's Bluff: the Mystery of the Book Darwin Never Finished by Robert Shedinger, see also amazon.com/Darwins-Bluff-Robert-Shedinger/dp/1637120370
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    25 分