Genetic sequencing is the process of determining the exact order of the nucleotides in a DNA or RNA molecule. Sequencing provides the complete "blueprint" of an organism's genetic code, and it's a critical tool in genetics, molecular biology, and medical research. Dr. Jonathon Hill develops innovative genomic and bioinformatic methods for gene expression analysis which has tremendous applications in cancer, early detection of chronic diseases, and personalized medicine

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Dr. Jonathon Hill is an Associate Professor of Cell Biology and Physiology at Brigham Young University and the Vice President of Science & Technology at Wasatch Biolabs. In this episode of Biomedical Frontiers, we dive into the field of genetic sequencing and genomics, how Jonathon built a company from the foundation of a novel gene sequencing technique, his research into congenital heart defects, and the future of the epigenetics field.

He is a Fulbright Scholar and a BYU Early-Career Teaching Award recipient, having received his MS in Molecular Biology from the University of Colorado Health Science Center and a PhD in Genetics and Developmental Biology from Columbia University. His company Wasatch Biolabs is working to move epigenetics from the lab to the clinic and his lab at BYU researches the molecular genetics of congenital heart defects by studying development of hearts in embryos.

Follow Dr. Jonathon Hill on Social Media

LinkedIn: https://www.linkedin.com/in/jonathon-t-hill/

Check out Dr. Jonathon Hill’s work at Wasatch Biolabs: https://www.wasatchbiolabs.com/

Director & Host: Dasha Tyshlek, StratCraft, Inc. www.strat-craft.com

Executive Producer: David Chen, Managing Director & Instructor of Engineering Design, UVA

Senior Producer: Hannah Moore, Associate Director, UVA Coulter

Design Director: Carolyn Wagner, Inc. & Link: carolynwagnerinc.com

Produced on behalf of Wallace H. Coulter Center for Translational Research at University of Virginia https://engineering.virginia.edu/centers-institutes/coulter-center-translational-research

What is innovation and why is it important to teach in an engineering program? Innovation has been defined as increasing value, which is increasing the benefits to cost ratio. Because innovation can be an ambiguous concept, it is important to develop a framework to guide the process. Since 2006, Dr. DiMeo has been coaching, consulting, and training processes of innovation, design thinking, and entrepreneurship for medical device innovation and healthcare impact.

Love this podcast? Write to us with ideas, feedback, and guest recommendations at biomedicalfrontiers@virginia.edu

Dr. Andrew DiMeo is a health innovator, biomedical engineer, design philosopher, and social entrepreneur. He began his career in New York, working on movies and TV shows, most notably The Sopranos. He has a BS in Physics and PhD in Biomedical Engineering and has spent most of his career teaching and practicing health innovation. In this episode of Biomedical Frontiers, we dive into Dr. DiMeo’s time teaching biomedical entrepreneurship at UNC and NC State, the teaching methodology and the philosophy for creating successful translational research classes, a new framework to help organizations innovate, and the future of STEM careers and education.

Dr. DiMeo has served as a Team Lead in NIH Programs, including RADx, ITAP, Blueprint MedTech, HIV Point of Care Testing, and C3i. He was previously a Professor of the Practice at UNC & NC State for 12 years where his students started multiple startups including 410 Medical, Contour Surgical, Augment Medical, Novocor Medical Systems, and MEDIC. He was co-founder of Gilero, founder of the NC Medical Device Trade Organization, and founder of CanvasGT, a SaaS startup acquired by Greenlight Guru. Today, you can find him mentoring the next generation of social entrepreneurs, working on his new venture, Hangar Dreys - a co-working concept in Raleigh, NC focused on addressing the loneliness epidemic.

Follow Dr. Andrew DiMeo on Social Media

LinkedIn: https://www.linkedin.com/in/ajdimeo/

IDEAL Biomedical Publication: https://medium.com/ideal-biomedical

Linktree: https://linktr.ee/andrewdimeo

Press Release about Springbok Analytics FDA approval:

https://www.prnewswire.com/news-releases/springbok-analytics-receives-fda-510k-clearance-for-muscleview-its-ai-muscle-health-analysis-from-a-rapid-mri-scan-302270603.html

Director & Host: Dasha Tyshlek, StratCraft, Inc. www.strat-craft.com

Executive Producer: David Chen, Managing Director & Instructor of Engineering Design, UVA

Senior Producer: Hannah Moore, Associate Director, UVA Coulter

Design Director: Carolyn Wagner, Inc. & Link: carolynwagnerinc.com

Produced on behalf of Wallace H. Coulter Center for Translational Research at University of Virginia https://engineering.virginia.edu/centers-institutes/coulter-center-translational-research

Microvessels are a crucial part of our body’s circulatory system. They're responsible for delivering the oxygen and nutrients to every cell in your body and are often devastated by diseases like Diabetes and Alzheimer's. Dr. Peirce-Cottler develops computational models and combines them with wet lab experiments to study how tissues heal after injury and to develop therapies for inducing tissue regeneration.

Love this podcast? Write to us with ideas, feedback, and guest recommendations at biomedicalfrontiers@virginia.edu

Dr. Shayn Peirce-Cottler the is Harrison Distinguished Teaching Professor and Chair of Biomedical Engineering, with secondary appointments in the Department of Ophthalmology and Department of Plastic Surgery at the University of Virginia (UVA). In this episode of Biomedical Frontiers, we dive into the history and future of microvascular research, the observed connection between Alzheimer's and diabetes, and the future healthcare applications of computational modeling.

Dr. Peirce-Cottler received Bachelor’s of Science degrees in Biomedical Engineering and Engineering Mechanics from The Johns Hopkins University and her Ph.D. in the Department of Biomedical Engineering at the University of Virginia. She has published over 125 peer reviewed papers and book chapters, is a fellow in both the American Institute for Medical and Biological Engineering College of Fellows (AIMBE) and the Biomedical Engineering Society (BMES). She was awarded the UVA School of Medicine’s Robert H. Kadner Award for Excellence in Graduate Teaching and Mentoring. Her courses in cell and molecular physiology and computational systems bioengineering are foundational to the BME undergraduate and graduate studies at UVA.

Follow Dr. Shayn Peirce-Cottler on Social Media

LinkedIn: https://www.linkedin.com/in/shayn-peirce-cottler-a70993/

Check out Dr. Peirce-Cottler’s work: https://www.peircecottlerlab.com/

Recent publications from Shayn’s lab: https://www.peircecottlerlab.com/publications

Check out Dr. Shannon Barker's page: https://engineering.virginia.edu/faculty/shannon-barker

Read about combining synthetic biology, computational modeling, and machine learning to design and build tissues: https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1010701

Director & Host: Dasha Tyshlek, StratCraft, Inc. www.strat-craft.com

Executive Producer: David Chen, Managing Director & Instructor of Engineering Design, UVA

Senior Producer: Hannah Moore, Associate Director, UVA Coulter

Design Director: Carolyn Wagner, Inc. & Link: carolynwagnerinc.com

Produced on behalf of Wallace H. Coulter Center for Translational Research at University of Virginia https://engineering.virginia.edu/centers-institutes/coulter-center-translational-research