Josephine K. Dermawan, MD, PhD, a soft tissue pathologist at Cleveland Clinic joins the Cancer Advances podcast to discuss the development of novel genomic risk stratification models for soft tissue and uterine leiomyosarcomas. Given the complexity and variety of sarcomas, accurately identifying subtypes is key to effective treatment. Listen as Dr. Dermawan explains the challenges of risk stratification and how genomic profiling enhances our ability to predict tumor behavior, leading to more precise treatment decisions.

Chair of the Department of Gastroenterology, Hepatology and Nutrition, Michelle Kang Kim, MD, PhD, joins the Cancer Advances podcast to discuss neuroendocrine tumors and carcinoid heart disease. Listen as Dr. Kim shares her expertise on this rare but increasingly prevalent type of cancer, the complexities of managing carcinoid heart disease, a condition seen in patients with metastatic neuroendocrine tumors, and the benefits of multidisciplinary care in treatment planning.

Breast Medical Oncologist, Erin Roesch, MD, joins the Cancer Advances podcast to discuss endocrine therapy for breast cancer in young patients. Listen as Dr. Roesch explains the key differences in treatment for premenopausal women, including the use of tamoxifen, ovarian suppression, and aromatase inhibitors.

Joshua Arbesman, MD, Dermatologist and Director of the Pigmented Lesion Clinic at Cleveland Clinic, joins the Cancer Advances podcast to talk about the genetic risks of melanoma. Listen as Dr. Arbesman delves into the inherited predispositions for melanoma, highlights key findings from his research on identifying high-risk patients and explains how genetic testing can help in early detection and personalized treatment.

Zeina Nahleh, MD, Cancer Center Director and Regional Chair of Hematology Oncology at Cleveland Clinic in Florida joins the Cancer Advances Podcast to discuss the latest breakthroughs in treating brain metastasis in breast cancer patients. Listen as Dr. Nahleh shares insights into the challenges of managing this complex condition, highlights key findings from her recent study, and emphasizes the critical role of combining local and systemic therapies. Discover what the future holds with emerging treatments and how they may improve patient outcomes in this evolving field.

Gregory Videtic, MD, Director of the Thoracic Radiation Oncology Program at Cleveland Clinic, joins the 200th episode of the Cancer Advances podcast to talk about neuroprotection in patients with small cell lung cancer. Listen as Dr. Videtic explains the findings of the NRG CC003 trial, which examined how hippocampal-sparing radiation could minimize memory-related side effects while maintaining cancer control.

The Cancer Advances podcast is joined by Ofer Reizes, PhD, the Laura J. Fogarty Endowed Chair for Uterine Cancer Research, and Roberto Vargas, MD, Gynecologic Oncologist and Program Director for the Gynecologic Oncology Fellowship to discuss their research on targeting CD55 to combat chemoresistance in ovarian cancer patients. Listen as they insights into the mechanisms behind chemoresistance, the challenges it presents in treatment, and the potential for innovative therapies to transform patient outcomes.

Arun D. Singh, MD, Director of Ophthalmic Oncology at Cleveland Clinic Cole Eye Institute, returns to the Cancer Advances podcast to discuss iris melanoma. Listen as Dr. Singh talks about the unique characteristics of this rare eye cancer, the latest advancements in diagnosis and treatment, including cutting-edge imaging techniques and the potential of machine learning. Tune in for this insightful discussion on this rare type of melanoma.