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Ep 114-"Fungal Infections in the ICU: Understanding Risks, Diagnosis, and Treatment"
- 2024/11/10
- 再生時間： 14 分
- ポッドキャスト
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サマリー
あらすじ・解説
Welcome to today’s episode, where we’ll dive into a critical topic in ICU care: the diagnosis and treatment of invasive fungal infections (IFIs) in critically ill patients who are not neutropenic. We’ll explore two common culprits of these infections—*Candida* and *Aspergillus*—and discuss what makes these infections especially challenging to diagnose and treat. To start, we’ll look at the risk factors that put patients at higher risk for invasive candidiasis (IC) and invasive aspergillosis (IA). From there, we’ll break down the clinical signs and symptoms that might suggest these fungal infections, even though they often present in non-specific ways. Diagnosing IC and IA is particularly tricky. Proven IC cases are rare, and a definitive diagnosis of IA can be elusive, especially without the ability to perform invasive testing on critically ill patients. We’ll discuss the different diagnostic tools and tests available, along with their limitations, and how clinicians approach the diagnostic workup for these infections. Finally, we’ll cover treatment strategies. Antifungal therapy is essential, but choosing the right first-line agents is crucial to achieving the best outcomes. We’ll also talk about therapeutic drug monitoring—why it’s necessary to balance efficacy with minimizing toxicity. So, if you’re ready to better understand IFIs in the ICU and how to manage these challenging infections, let’s get started!