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How Resilience Works in the Brain: The Neuroscience Behind Mental Toughness Resilience is often described as the ability to bounce back from adversity, maintain emotional stability in difficult situations, and thrive in the face of challenges. But how exactly does this process unfold in the brain? Mental resilience isn’t just a psychological concept; it’s deeply rooted in the biological and neurological structures of the brain. Thanks to advances in neuroscience, we now have a clearer understanding of how resilience works at a neural level, and how certain brain regions and processes play key roles in fostering mental toughness. Let’s take a deeper look at the brain mechanisms involved in resilience, and how you can actively build mental strength by understanding the brain’s role.