High prescription costs are a major barrier to the optimal treatment of many health conditions. Prescribers need tools to help patients find the lowest drug costs. Author Hussain S. Lalani, MD, MPH, MSc, of Brigham and Women's Hospital and Harvard Medical School joins JAMA Senior Editor Anne R. Cappola, MD, ScM, to discuss "Strategies to Help Patients Navigate High Prescription Drug Costs."

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• Strategies to Help Patients Navigate High Prescription Drug Costs
• Strategies to Help Patients Afford Their Medicines in the US

Even though highly effective medications are currently available to prevent HIV, there are about 1.3 million new infections worldwide each year. Monica Gandhi, MD, MPH, of the University of California San Francisco joins JAMA Senior Editor Karen E. Lasser, MD, MPH, to discuss preexposure prophylaxis (PrEP) for HIV.

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• Preexposure Prophylaxis (PrEP) for HIV
• What Is Doxycycline Postexposure Prophylaxis?

In July 2023, the US Food and Drug Administration (FDA) approved Opill, a daily progestin-only oral contraceptive for over-the-counter sale to people of all ages. Daniel Grossman, MD, discusses this and more with JAMA Associate Editor Melissa A. Simon, MD, MPH.

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• Over-the-Counter Oral Contraceptives
• Over-the-Counter Oral Contraceptive Pills
• Over-the-Counter Progestin-Only Oral Contraceptives