『STEM-Talk』のカバーアート

STEM-Talk

STEM-Talk

著者： Dawn Kernagis and Ken Ford
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The most interesting people in the world of science and technologyFlorida Institute for Human and Machine Cognition 代替医療・補完医療 博物学 科学 自然・生態学 衛生・健康的な生活
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  • Episode 199: Ken and Dawn respond to listener questions on aging, meat consumption and dementia, genetic testing, AI, exercise, a lunar mission and much more

    Episode 199: Ken and Dawn respond to listener questions on aging, meat consumption and dementia, genetic testing, AI, exercise, a lunar mission and much more
    2026/09/15
    Today we have the second of a two-part AMA. In part one, episode 198, we covered a multitude of listener questions about AI, which lately seems to dominate the news cycle. Other than one AI question that managed to sneak in, today’s AMA features a wide range of questions on a number of topics other than artificial intelligence. Today, Ken and Dawn respond to listener questions that range from: — Whether there’s a critical difference between whey protein powders and ready-to-drink protein shakes? — Is there a sweat spot for how much time a person should spend on resistance training during a week? — Ken’s thoughts on a paper that looked at whether higher meat consumption could be associated with a lower risk of dementia among people carrying the APOE ε4 gene variant. — What kind of Pandora’s box will we open if parents start doing genetic tests on their infants to see if their children have, say, the APOE ε4 gene variant? — Will NASA will be able to meet its target date of sending astronauts back to the Moon by 2028? — And a lot more. Show notes; [00:03:05] A listener asks Ken about the 2019 Trim study by Gregory Fahy and colleagues in Aging Cell, which reported reversal of epigenetic aging and signs of thymic regeneration in nine healthy men treated with the growth hormone, DHEA, and metformin. [00:06:56] Ken responds to a question about the market being flooded with protein supplements. The listener asks if whether there’s a critical difference between whey protein and ready-to-drink protein shakes, and if there are any specific products he recommends. [00:10:50] A listener asks Ken about a recent article in Nature Reviews Neuroscience titled: [00:15:26] A listener asks Ken about a Chinese company called Moonshot AI and its open-weight model, Kimi K3. The listener references Gary Marcus who anticipates that the power of this model paired with the open-weight design will have immense implications. The listener asks for Ken’s take. [00:25:56] A listener mentions that they’ve heard that Ken likes to tell graduate students a fable about a rabbit pursuing their Ph.D. A listener asks Ken if he would share the fable. [00:30:15] A listener asks Ken about a study published in Jama Network Open by Norgren and company which suggests that higher meat consumption may be associated with lower Alzheimer’s risk for people carrying the APOE 4 gene variant, the strongest common genetic risk factor for late onset Alzheimer’s. [00:38:24] A listener mentions in their question for Ken that the Department of Health and Human Services recommends at least 150 minutes of moderate exercise per week, but this recommendation does not break down how much of that time should be spent on aerobic versus strength training. The listener goes on to mention a study in the that looked at identifying this sweet spot for resistance exercise, finding that between 90-119 minutes per week of weightlifting was associated with a 13 perent lower risk of premature death and a 27 percent reduction in neurological disease mortality, particularly Alzheimer’s. The listener also mentions that they are aware of IHMC’s ongoing clinical trial looking at the ability of exercise to mitigate the hallmarks of aging in people over 60 years old. The listener asks if this study is similarly trying to identify a sweet spot for resistance exercise, and if Ken has any recommendations on this topic. [00:46:32] Another listener mentions that they really enjoyed our interview with Doug Cooke on the Artimis II mission (episode 195), as well as our interview with Mike Griffin and Lisa Porter about NASA’s plan to return to the moon (episode 189). The listener goes on to mention that since then a Blue Origin rocket, one of the companies responsible for building a lunar lander, exploded on the launch pad in Florida. The listener asks if Ken is he’ still skeptical about the Artemis III mission architecture and timeframe in light of the recent news. [00:54:37] A listener asks Ken for his thoughts on the growing research efforts to investigate the feasibility of doing genetic testing on infants to identify their predisposition to specific diseases such as Alzheimer’s. [01:01:57] A listener asks for Kens thoughts on a study of creatine’s effects on physically active vegans. The study reported that 4 weeks of creatine supplementation improved lower-body power, especially jump height and flight time. But they did not find improvements in strength tests. [01:08:10] A listener asks for Ken’s thoughts on a recent White House report “Science: A New Golden Age”, which argues that the American scientific enterprise needs to be reformed and that agencies like NSF have become overly bureaucratic, slow, and risk averse. Links: Learn more about IHMC STEM-Talk homepage Ken Ford bio Ken Ford Wikipedia page
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    1 時間 18 分
  • Episode 198: Blessing or curse? Dawn grills Ken on listeners’ toughest AI questions in this all-AI AMA

    Episode 198: Blessing or curse? Dawn grills Ken on listeners’ toughest AI questions in this all-AI AMA
    2026/08/12
    Today we have an Ask Me Anything episode that focuses on artificial intelligence. For the past year, AI has dominated the headlines. Perhaps because there’s so much media and public interest, as well as paranoia, about AI, listeners have been flooding our mailbox with AI-related questions. So, today’s AMA is an exclusive focused on artificial intelligence. For our listeners who have been sending questions about ketamine; NASA’s Artemis mission to the Moon; or whether high meat consumption leads to dementia; fear not, because we will follow up today’s episode in a few weeks with a second round of AMA. Dr. Ken Ford will be answering today’s AI questions. He has been working in AI since the 1980s and is a Fellow of the Association for the Advancement of Artificial Intelligence. As a result, he is well-positioned to help us today to separate real advances in AI from hype, panic and science fiction. If you have questions for Ken and Dawn after listening to today’s episode, or any episode of STEM-Talk, email your questions to STEM-Talk producer Randy Hammer at rhammer.ihmc.org. Show notes: [00:03:15] Dawn opens our AMA episode on AI with a listener question for Ken on whether AI companies should be protected under section 230 of the U.S. Communications Decency Act. [00:08:03] Following up on the previous question, a listener asks if Ken foresees a day where laws and courts will designate AI as a judicial person, in the same way that corporations have rights under the legal doctrine of corporate personhood. [00:10:55] A listener asks Ken for his thoughts on a recent article published in the Atlantic titled “The Data-Center Panic is Overblown: Critics are Inflating the Costs.” [00:16:09] A listener asks Ken a question regarding episode 171 of STEM-Talk, in which Ken discussed a June 2024 report by Leopold Aschenbrenner which predicted rates of growth in both compute resources and power requirements for AI data centers. The listener asks how well these predictions have held up in the following year. [00:22:19] Another listener question about data centers asks Ken what his thoughts are on the notion of solving the electricity costs and cooling requirements for data centers by building them in orbit and powering them via solar energy. [00:30:07] Moving on to the applications of AI, Peter Attia recently wrote about a study out of Harvard that suggests that today’s large language models perform extremely well on medical licensing exams and often arrive at the correct diagnosis yet still struggle with differential diagnosis. The listener asks what this means about the use of AI in medicine. [00:36:53] A listener asks Ken about repeated public statements by Anthropic’s CEO that their AI models, and those expected in the future, are already powerful and dangerous enough to justify concern, while at the same time Anthropic and other leading AI companies are continuing to employ these systems and cautioning governments against regulation that could slow down innovation. The listener asks Ken how to resolve this contradiction. [00:45:18] A listener writes that in a previous AMA, STEM-Talk episode 184, Ken objected to the use of the word hallucination to describe errors made by large-language models and asks Ken to expound on this. [00:53:28] A listener asks Ken whether current AI models are evolving from being fundamentally prediction engines to being able to truly understand and reason, or if they are just becoming better and more convincing prediction engines. [00:59:37] A listener writes to Ken, mentioning that a few years ago, a thousand technology experts and researchers signed a letter urging AI labs and executives to pause the development of highly advanced AI systems and tools. This letter, drafted through the not-for-profit Future of Life Institute, warned that AI developers were locked in an out-of-control race to develop and deploy ever more powerful digital minds that no one, not even their creators, can understand, predict or reliably control. The listener also states that they learned recently that ChatGPT 5 was programmed using an earlier version of ChatGPT. If the concerns of tech leaders are to be taken seriously, the listener wonders if it is a good idea to have earlier versions of ChatGPT programing later versions of ChatGPT? [01:07:45] A listener asks Ken about the process of training smaller AI models from larger models, a process called distillation. The listener asks how this process works and if this is a way for the cost of training large models to benefit everyone. [01:14:56] A listener asks Ken what it means for China’s Open Weight GLM 5.2 to be reported to have achieved near parity with Anthropic’s Mythos. On several cyber security and vulnerability discovery benchmarks, it seems alarming that GLM 5.2 is operating at roughly 1/6th the cost and remaining openly available for download and deployment. [01:22:34] A listener writes that they recently heard a story about ...
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    1 時間 39 分
  • Episode 197: Scott Sherr discusses hyperbaric oxygen therapy, methylene blue, and more

    Episode 197: Scott Sherr discusses hyperbaric oxygen therapy, methylene blue, and more
    2026/07/15
    Today we have Dr. Scott Sherr, an internal medicine physician who specializes in Hyperbaric Oxygen Therapy. Scott is the director of Integrative Hyperbaric Medicine and Heath Optimization at Hyperbaric Medical Solutions. It is a division of Hyperbaric Medical Solutions, an independent, hyperbaric oxygen therapy provider that aims to educate people about the benefits of hyperbaric oxygen therapy via telemedicine consulting. He also is COO of Troscriptions, which provides physician-formulated products including popular methylene blue products. In today’s interview, Scott talks about how he uses Hyperbaric Oxygen Therapy (HBOT) to treat a number of health conditions. He also shares how he incorporates methylene blue into some of his treatment strategies and explains how HBOT is now being used as a complementary treatment for autoimmune diseases by helping reduce inflammation, improve blood flow and support immune function. Show notes: [00:03:29] Dawn tells Scott that she heard a story that Scott had his spine adjusted when he was just five minutes old. She asks Scott if he can share what happened. [00:04:15] Dawn mentions that Scott grew up in New York on Long Island and that as a child he spent a lot of time at his father’s chiropractic office. Dawn asks Scott about his father and his practice. [00:05:38] Ken notes that Scott was into sports as a kid and asks him to talk about his childhood and what he was like as a kid. [00:07:09] Dawn notes that after high school, Scott left New York for the West Coast, landing at UCLA. Dawn asks Scott to talk about what led him there. [00:08:00] Dawn explains that Scott initially started to major in biology but quickly changed majors. Scott explains why he changed majors. [00:08:41] Dawn asks Scott why he chose to attend the University of Maryland for medical school after graduating from UCLA. [00:09:26] Dawn asks Scott about the story of how he met his wife at the University of Maryland. [00:09:50] Dawn pivots back to Scott’s love of music, mentioning that Scott and three other medical school students at Maryland formed a band called The Airport Rocking Chairs. Scott describes how the band came together and how they performed at gigs around the Baltimore/D.C. area. [00:11:16] Ken asks Scott to talk about how his early ambition upon entering medical school was to find a way to bridge the gap between conventional and alternative/chiropractic medicine. [00:12:54] Ken explains that in Scott’s third year of medical school, he did rotations at the University Shock and Trauma Facility. Ken asks Scott to talk about why this was such an important experience for Scott. [00:14:32] Dawn explains that hyperbaric chambers are used to treat injuries like necrotizing fasciitis and severe wounds. Dawn asks Scott to talk about finding a hyperbaric chamber in the basement of the University Shock and Trauma Facility and how that led to his fascination with the potential for hyperbaric oxygen therapy. [00:15:51] Dawn asks Scott to talk about how his initial research on hyperbaric therapies led him to conclude that they were being vastly underutilized in conventional medicine. [00:16:31] Dawn mentions that people are likely familiar with hyperbaric oxygen therapy (HBOT) in terms of treating divers suffering from decompression sickness. She asks Scott to give a primer on the mechanisms by which HBOT affects the body and why it has potential to treat other conditions besides decompression sickness. [00:19:38] Ken asks Scott to talk more about other conditions, both acute and chronic, that HBOT might be helpful in treating. [00:22:51] Dawn asks about Scott’s experience as a hospitalist, which is an internal medicine physician who acts as a primary care physician in a hospital, and how this experience gave him a unique perspective on the strengths and limitations of modern medicine. [00:25:13] Ken asks Scott if it’s fair to say that his experience as a hospitalist was foundational in developing his understanding of patient care and healthspan. [00:26:51] Dawn explains that when Scott’s wife received a fellowship at Stanford University, Scott eventually left his career as a hospitalist to serve as the medical director for a hyperbaric medicine facility in the San Francisco Bay area. Dawn asks Scott to talk about how this experience deepened his understanding and expertise in hyperbaric oxygen therapy. [00:28:26] Ken asks Scott to talk about his relationship with Dominic D’Agostino, who was our recent guest on STEM-Talk episode 196, and who is very active in the field of hyperbaric oxygen therapy. [00:30:48] Dawn mentions that during Scott’s work as a hospitalist, he began to develop a more integrated approach to hyperbaric medicine, taking nutritional status, sleep patterns, mitochondrial function, and a number of other factors into consideration. Doing this work, Scott noticed that a number of patients would require weeks or months of preparation before beginning HBOT, ...
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    1 時間 27 分
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