As researchers continue to look for new ways to test therapeutics in vitro, the field of biomedical engineering is offering new microphysiological systems that can reduce the need for animal models. Hear from Jeffrey Borenstein, Director of the Biomedical Engineering Centre at Draper, as he explains how it works, ways to expedite its access, and the benefits they will ultimately bring to patients.

Show Notes 
 

The Coming of Age of Organ-on-a-Chip technology

Sounds of Science E76: Multi-Organ Chip Systems

Charles River Joins Consortium to Advance Organ-on-a-Chip Technology

Bold New Approached: The Future of Organoid Intelligence

Organoids Evolve from Academic Marvel to Industrial Tool

I am joined by Raphael (Ralph) Malbrue, Director & Attending Veterinarian, Center for Comparative Medicine, University of Virginia; and Christina (Winnie) Winnicker, Executive Director for Laboratory Animal Medicine for Charles River. Both bring a fresh perspective to the questions of how to improve diversity in veterinary medicine, how to inform new graduates of previously unconsidered career paths in lab animal medicine, and what kind of specialties are in demand in the industry now.

Piotr Kosla, founder of the PACS2 Research Foundation, joins us to discuss his personal motivation to develop the first treatment for Development and Epileptic Encephalopathy 66 (PACS2 Syndrome), how cell painting assays are being used to repurpose a treatment for this condition, what the future holds for research in this area, and how you can help contribute to his mission.

Show Notes

• PACS2 Research Foundation
• Eureka Blog | Drug Repurposing Through Cell Painting Could Treat Rare Disease
• ASO Screening Services
• Gene Therapy Services
• Art of Science: Cell Painting
• Free for Life: The Story of n-Lorem Foundation