The San Francisco 49ers are reeling as star wide receiver Deebo Samuel is sidelined with a calf strain, a blow to their offensive strategy. Can Brandon Aiyuk rise to the occasion and fill the void left by Samuel's absence?

This episode tackles the 49ers' offensive line struggles, spotlighting the pressures allowed by Trent Williams and Colton McKivitz. We also explore Fred Warner's standout performances, fueling his candidacy for Defensive Player of the Year. Plus, get an in-depth analysis of the 97-yard touchdown pass from Sam Darnold to Justin Jefferson, dissecting the defensive breakdown and execution.

San Francisco 49ers fans are treated to daily news and analysis with Locked On 49ers, hosted by football analyst Brian Peacock and former NFL/AFL cornerback Eric Crocker.

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