In this powerful and inspiring bonus episode, we delve into the remarkable journey of Shruti Kothari, a 34-year-old actress and stroke survivor.

On March 7, 2020, just before the pandemic shook the world, Shruti experienced a stroke while hosting friends at her apartment. Her left side went numb, and thanks to a quick-thinking friend trained in recognizing stroke symptoms, paramedics were called immediately.

Shruti’s story is not just one of survival but thriving against all odds. She talks about her rehabilitation process, an innovative program that helped her regain movement in her arm, and her determination to continue her acting career. Despite the challenges, Shruti’s optimism and drive to give back to the community shine through.

Additional Resources
UHN's Stroke Prevention Clinic
Dr. Pikula was interviewed in the Your Complex Brain episode "The Rise of Stroke in Young Adults"
UHN Foundation video "Shruti's journey back to the stage, with some help from Team UHN"
Heart and Stroke Foundation of Canada – Women's Digital Hub
World Stroke Academy podcast featuring Dr. Lindsay

The Your Complex Brain production team is Heather Sherman, Jessica Schmidt, Dr. Amy Ma, Kim Perry, Alley Wilson, Sara Yuan, Meagan Anderi, Liz Chapman, and Lorna Gilfedder.

The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.

Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembil

To get in touch, email us at krembil@uhn.ca or message us on social media:
Instagram - @krembilresearch
Twitter - @KBI_UHN
Facebook - https://www.facebook.com/KrembilBrainInstitute

Thanks for listening!

In this bonus episode, we dive deeper into the lived experience of Matthew Cote, a teacher and advocate for those living with learning disabilities, including reading disabilities. Matthew shares his personal journey, detailing how his reading disability impacted his early years, from struggling to decode words and feeling isolated to the turning point when he received assistive technology that transformed his learning experience. He also talks about the crucial role of support from his family, particularly his mother, and his teacher who helped him believe in himself.

Additional Resources
Dr. Cathy Barr's UHN Research website
UHN Foundation story featuring Dr. Cathy Barr – "Reading the Genome"
Sick Kids Empower Reading & Learning Group
Learning Disabilities Association of Ontario

The Your Complex Brain production team is Heather Sherman, Jessica Schmidt, Dr. Amy Ma, Kim Perry, Alley Wilson, Sara Yuan, Meagan Anderi, Liz Chapman, and Lorna Gilfedder.

The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.

Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembil

To get in touch, email us at krembil@uhn.ca or message us on social media:
Instagram - @krembilresearch
Twitter - @KBI_UHN
Facebook - https://www.facebook.com/KrembilBrainInstitute

Thanks for listening!

Neurofibromatosis, also known as NF, is one of the most common genetic disorders affecting about 1 in 3000 people globally. However, little is known about the condition causing it to often be misdiagnosed or go undiagnosed. Neurofibromatosis causes different types of tumors to form in various parts of the body.

In this bonus episode, Dr. Ryan Thomas, a family physician and Clinical Associate at UHN's Elisabeth Raab Neurofibromatosis Clinic—the only adult NF clinic in Canada—shares his personal journey with NF. Diagnosed in his late twenties, Dr. Thomas underwent a life-changing surgery to remove a large tumor in his chest, just two months before his wedding. His experience provides a unique perspective on the condition, allowing him to connect deeply with his patients.

Additional Resources
Canadian First : UHN Opens Multidisciplinary Clinic on Genetic Disorder
Elisabeth Raab Accelerator of Science to End Neurofibromatosis
Neurofibromatosis Ontario
Dr. Gelareh Zadeh's lab – link to more info about the Elisabeth Raab Neurofibromatosis Clinic
Children's Tumour Foundation

The Your Complex Brain production team is Heather Sherman, Jessica Schmidt, Dr. Amy Ma, Kim Perry, Alley Wilson, Sara Yuan, Meagan Anderi, Liz Chapman, and Lorna Gilfedder.

The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.

Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembil

To get in touch, email us at krembil@uhn.ca or message us on social media:
Instagram - @krembilresearch
Twitter - @KBI_UHN
Facebook - https://www.facebook.com/KrembilBrainInstitute

Thanks for listening!

Parkinson's disease is the fastest-growing neurological condition in the world, affecting over 100,000 Canadians and 12,000 new cases diagnosed every year. In this bonus episode of Your Complex Brain, we explore the transformative power of exercise in managing Parkinson's symptoms and possibly slowing the disease’s progression.

Join us as we hear from Steven Iseman, who was diagnosed with Young Onset Parkinson’s Disease at 48. Now 58, Steven shares his remarkably journey from hiding his diagnosis to becoming a passionate advocate for Parkinson’s awareness and the benefits of exercise. Learn how he co-founded the Rigid Riders cycling club and the Spinning Wheels Tour, cycling 8,000 km across Canada to connect with and support others living with Parkinson’s. Steven’s story is one of resilience, community and the relentless pursuit of a better life despite his diagnosis. Discover how exercise has not only helped Steven manage his symptoms but also given him a renewed sense of purpose and direction.

Additional Resources
UHN Movement Disorders Clinic website
Kalia Labs website
Video: Dr. Lorraine Kalia on why she studies Parkinson's
Video: Dr. Lorraine Kalia Discusses the Latest in Parkinson's Research on TVO's The Agenda
Video: The Rigid Riders Story
Spinning Wheels Cycling Tour

The Your Complex Brain production team is Heather Sherman, Jessica Schmidt, Dr. Amy Ma, Kim Perry, Alley Wilson, Sara Yuan, Meagan Anderi, Liz Chapman, and Lorna Gilfedder.

The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.

Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembil

To get in touch, email us at krembil@uhn.ca or message us on social media:
Instagram - @krembilresearch
Twitter - @KBI_UHN
Facebook - https://www.facebook.com/KrembilBrainInstitute

Thanks for listening!

In this bonus episode of Your Complex Brain, we hear from John Ruffolo, Founder and Managing Partner of Maverix Private Equity, who shares his personal journey of surviving a life-threatening cycling accident in 2020 that left him with a severe spinal cord injury. John recounts the harrowing moments following the accident, his extensive surgeries, and his remarkable recovery journey. Despite being diagnosed with the most severe grading of spinal cord injury, John’s relentless spirit and dedication to physical therapy have led to astonishing improvements in his mobility.

Featuring:
John Ruffolo is the Founder and Managing Partner of Maverix Private Equity, a private equity firm focused on technology-enabled growth and disruption investment strategies. Maverix invests in health and wellness, financial services, transportation and logistics, live, work, play and learn and retail. As an active board member in the profit and not-for-profit sectors, John works with many leading innovative organizations and has been recognized as Canada's #1 of 100 Most Powerful Business People by Canadian Business Magazine and was selected as one of Toronto's 50 Most Influential People by Toronto Life. He is currently living with a spinal cord injury.

Additional Resources
UHN's Spinal Cord Injury Clinic
Dr. Fehlings' Laboratory for Neural Repair and Regeneration website
Dr. Fehling's interview on Season 1 of Your Complex Brain, 'Revolutionary Advances in Spinal Cord Injury'
PSI Foundation feature story on Dr. Laureen Hachem
Toronto's Top Grad Dreams Big – Toronto.com feature story on Dr. Laureen Hachem as a high school student
The Globe and Mail feature story on John Ruffolo

The Your Complex Brain production team is Heather Sherman, Jessica Schmidt, Dr. Amy Ma, Kim Perry, Alley Wilson, Sara Yuan, Meagan Anderi, Liz Chapman, and Lorna Gilfedder.

The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.

Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembil

To get in touch, email us at krembil@uhn.ca or message us on social media:
Instagram - @krembilresearch
Twitter - @KBI_UHN
Facebook - https://www.facebook.com/KrembilBrainInstitute

Thanks for listening!

In this bonus episode of Your Complex Brain, we delve into the world of dementia care with Maria Martinez, a dedicated social worker at UHN’s Memory Clinic, part of the Krembil Brain Institute. With nearly 25 years of experience, Maria shares her journey from studying anthropology and sociology to becoming a vital support for patients living with dementia and their families.

Maria highlights the unique challenges faced by those dealing with rare dementias and early-onset cases, emphasizing the importance of personalized support and the significant financial burdens these families often encounter.

Despite the challenges, Maria finds hope and fulfillment in her work, learning continuously from the resilient families she supports. This episode offers a heartfelt glimpse into the daily efforts of a social worker dedicated to making a difference in the lives of those affected by dementia.

Featuring:
Maria Martinez has been a social worker for nearly 25 years. Most recently, she has worked with the team at UHN’s Memory Clinic, helping patients living with Alzheimer’s and dementia, and their families, navigate their diagnosis and community support.

Additional resources:
Dr. Carmela Tartaglia’s interview on EP 1 of Your Complex Brain – ‘The Quest to Solve the Concussion Problem’
Risk Factors for Alzheimer’s and Dementia (video)
UHN Memory Clinic
Schlegel-UW Research Institute for Aging (RIA)
Dr. Laura Middleton’s research project - DREAM (Dementia Resources for Eating, Activity, and Meaningful Inclusion
Dr. Laura Middleton’s research project - DICE (Dementia Inclusive Choices for Exercise)

The Your Complex Brain production team is Heather Sherman, Jessica Schmidt, Dr. Amy Ma, Kim Perry, Alley Wilson, Sara Yuan, Meagan Anderi, Liz Chapman, and Lorna Gilfedder.

The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.

Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembil

To get in touch, email us at krembil@uhn.ca or message us on social media:
Instagram - @krembilresearch
Twitter - @KBI_UHN
Facebook - https://www.facebook.com/KrembilBrainInstitute

Thanks for listening!

Loud, disruptive snoring could be (but isn’t always) a sign of sleep apnea, a common condition in which breathing may stop and start many times throughout the night.

You may be aware that sleep apnea can disrupt your sleep and cause fatigue, but did you know that it can also impact your heart, your brain – even your sex drive?

In today’s episode, we discuss the health risks of undiagnosed sleep apnea and why, if you’re having trouble sleeping or staying awake during the day, if you’re experiencing morning headaches, mood changes or difficulty focusing, you should consider getting a sleep test.

Featuring:
Dr. Douglas Bradley - Director of UHN’s Centre for Sleep Health and Research, at Toronto General Hospital.
Dr. Frances Chung - Anesthesiologist and Clinician Investigator with UHN’s Krembil Brain Institute; Inventor of the STOP-Bang Questionnaire, a new screening tool for sleep apnea that’s being used around the world.
Carmen Chu – Fundraising professional and cancer survivor, who was recently diagnosed with sleep apnea.

Additional resources:
UHN’s Centre for Sleep Health and Research
Dr. Frances Chung named UHN Inventor of the Year
Dr. Douglas Bradley featured in KITE Research spotlight: Use of non-invasive breathing device to alleviate obstructive and central sleep apnea improves quality of life

The Your Complex Brain production team is Heather Sherman, Jessica Schmidt, Dr. Amy Ma, Kim Perry, Alley Wilson, Sara Yuan, Meagan Anderi, Liz Chapman, and Lorna Gilfedder.

The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.

Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembil

To get in touch, email us at krembil@uhn.ca or message us on social media:
Instagram - @krembilresearch
Twitter - @KBI_UHN
Facebook - https://www.facebook.com/KrembilBrainInstitute

Thanks for listening!

At UHN’s Krembil Brain Institute, we have cared for many patients living with an extreme and heartbreaking facial pain disorder called trigeminal neuralgia. Patients often describe the pain as a lightning bolt to the face, or an electric shock. Some talk about the impact the disease has had on their family & relationships, including not being able to hug their loved ones, or kiss their children goodnight.

In today’s episode, we discuss how AI is helping researchers look for patterns and clues to treat patients living with trigeminal neuralgia and other chronic pain disorders.

Featuring:
Dr. Mojgan Hodaie – Neurosurgeon and senior scientist with UHN’s Krembil Brain Institute and the Greg Wilkins-Barrick Chair in International Surgery at UHN. Dr. Hodaie is also a Professor and the Postgraduate Medical Education Director for the Department of Surgery, at the University of Toronto’s Temerty Faculty of Medicine. Her surgical practice and research laboratory are dedicated to unraveling the underpinnings of the severe pain condition of trigeminal neuralgia, using advanced brain imaging technology. Her interest and dedication to education spans local, national and international activities.

Adriana Salazar - Graduated from The University of Western Ontario with a Bachelor of Management and Organizational Studies (BMOS) and has worked in the Finance Department at a law firm for the past 9 years. She is happily married and has a lovely daughter who just finished her first year of school. In her off time, she enjoys traveling back home to Colombia to see her family, painting in watercolours, and reading James Patterson novels in her hammock.

Additional resources:
Dr. Hodaie was interviewed on Season 1 of Your Complex Brain – “The most painful brain disease you’ve never heard of”
Toronto neurosurgeon marks 1,000th operation treating 'excruciating' facial pain syndrome
Dr. Hodaie recounts her journey from new immigrant to neurosurgeon (video)
Brain Aging in Fast Forward (UHN Research article)
Dr. Hodaie was a featured speaker at KBI’s first-ever ‘International Day of Women and Girls in Science’ event (video)

The Your Complex Brain production team is Heather Sherman, Jessica Schmidt, Dr. Amy Ma, Kim Perry, Alley Wilson, Sara Yuan, Meagan Anderi, Liz Chapman, and Lorna Gilfedder.

The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.

Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembil

To get in touch, email us at krembil@uhn.ca or message us on social media:
Instagram - @krembilresearch
Twitter - @KBI_UHN
Facebook - https://www.facebook.com/KrembilBrainInstitute

Thanks for listening!