検索キーワード： 遺伝学

Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome - an enormous molecular machine made up of a million atoms - that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases. 

By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only 24, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science's greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries.

In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field is horizontal gene transfer (HGT), or the movement of genes across species lines. For instance, we now know that roughly eight percent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection - a type of HGT. In The Tangled Tree David Quammen chronicles these discoveries through the lives of the researchers who made them.

A preeminent geneticist hunts the Neanderthal genome to answer the biggest question of them all: what does it mean to be human? What can we learn from the genes of our closest evolutionary relatives? Neanderthal Man tells the story of geneticist Svante Pbo’s mission to answer that question, beginning with the study of DNA in Egyptian mummies in the early 1980s and culminating in his sequencing of the Neanderthal genome in 2009.

With rapid advances in genomic technologies, genetic testing has become a key part of both clinical practice and research. Scientists are constantly discovering more about how genetics plays a role in health and disease, and healthcare providers are using this information to more accurately identify their patients' particular medical needs. Genetic information is also increasingly being used for a wide range of non-clinical purposes, such as exploring one's ancestry.

In recent years, as companies like 23andMe and Ancestry.com have made genetic testing available across the globe, it has become relatively simple to find out where your ancestors came from. But acclaimed geneticist Pierre Zalloua believes that these test results have led to a dangerous oversimplification of what one’s genetic heritage means. People have conflated genetic ancestry with other ways of defining themselves such as “origin,” “ethnicity,” and even “race” but give no attention to the complexities that underlie these concepts.

With genetics and genetic engineering receiving almost daily coverage in the media, this audiobook is an introduction for general listeners who wish to know more about a science that is changing our world. Starting with the history of genetics, from primitive breeding programmes to Mendel's Law, and moving on to a full explanation of genetics and its role in our future, this is a comprehensive survey of genetics past, present and future.

Entdecken Sie die Möglichkeiten, die sich durch die Verbindung von Wissenschaft und Naturheilkunde eröffnen, und erfahren Sie, wie Sie mit Hilfe von ätherischen Ölen Ihr Wohlbefinden steigern können. Ein glückliches, gesundes und erfülltes Leben liegt in Ihren Händen.

With so much variation that can be handed down genetically, for better or worse, the way we understand our biology holds huge importance for how we understand our world and one another, including the biggest questions of our day, such as social inequality. Eye-opening and profound, Adaptable is a revolutionary reappraisal of an overlooked science.

The Apples, Amazons and Googles of the next few decades will be biotech companies. The tech companies of the last few years have changed how we do things but the businesses driving the biotech revolution are about making life better. These companies will solve many of our most intractable problems: cancer, dementia, diabetes, elderly care, mental health challenges, even power generation and agricultural production. Biotech will mean that we can live far better, safer, healthier, wealthier, happier, and longer lives.

Over 500,000 years ago, a single gene mutated. It spread over time, becoming critical in the journey transforming our earliest ancestors into fully modern humans, capable of navigating the entire planet and beyond. Then just a few thousand years ago, humans gradually outsourced knowledge to writing, and we displaced art and music from the heart of learning. This is the extraordinary story of the discovery of a supergene that makes us uniquely human.

Los genes no son los responsables de la desigualdad pero llevan impresas las marcas que ha dejado a lo largo de nuestra historia. La creciente desigualdad en el siglo XXI es un grave problema social y sus causas y consecuencias provocan debates y controversias que implican desde agentes sociales y políticos hasta economistas. En Desigualdad, Carles Lalueza-Fox ofrece una visión totalmente nueva de este tema al examinar las huellas genéticas dejadas por la desigualdad en los humanos a lo largo de su historia.

¿Qué tiene de malo manipular nuestra naturaleza? ¿Dónde están las líneas rojas, si las hay? El filósofo Michael Sandel trata de responder a esta pregunta a través de un ameno pero profundo repaso del campo de la bioética.

Alejandra Ponce, experta en nutrigenómica, nos advierte que, contrario a lo que la medicina tradicional ha dictado, no es correcto seguir recomendaciones generales: hay que buscarun plan de alimentación adecuado para tus genes, de manera que goces hoy de una vida sana y que llegues a la vejez sin enfermedades. Aunque estamos programados genéticamente para presentar ciertos padecimientos, la combinación de una nutrición personalizada y un estilo de vida saludable hace posible retrasarlos o incluso silenciarlos para siempre.

A tiny mutation on the X chromosome can shape a family’s history. Passed down from a “carrier” parent to a child, fragile X syndrome is the most common inherited cause of intellectual disability and autism. Beyond that—and a rarity among genetic disorders—some fragile X carriers not only transmit the mutation, but also experience related conditions themselves.

Die CRISPR-Methode und die Zukunft der Medizin. Was macht die Natur, wenn ein neuer Feind auftaucht? Sie findet eine neue Strategie. Wenn eine Bakterie von einem Virus attackiert wird, verteidigt sie sich beispielsweise, indem sie ihre genetische Struktur ändert. Doch wie können diese Mechanismen nachgewiesen werden? Und welchen Nutzen hat dieses Wissen für die Medizin? Der Amerikanerin Jennifer Doudna und der Französin Emmanuelle Charpentier sind bahnbrechende Erkenntnisse im Bereich der Biochemie gelungen.

An almost limitless archive of our history lies hidden inside our bodies, and this book traces the ancient story of Scotland from that scientific viewpoint. The mushrooming of genetic studies, of DNA analysis, is rewriting history in spectacular fashion. In Scotland: A Genetic Journey, Alistair Moffat explores the history that is printed on our genes, and in a remarkable new approach, uncovers the detail of where Scots are from, where they have journeyed, and who they are - and in so doing, vividly colors in a DNA map of Scotland.

The field of biotechnology has evolved over the past four decades, developing medicines which are curing diseases. But this journey of success has been tough and arduous, built upon the shoulders of major failures.

Une extraordinaire histoire collective dont nous sommes tous les héritiers ! Les gènes sont une fascinante machine à remonter le temps depuis que nous savons faire "parler" non seulement l'ADN des Sapiens actuels, mais aussi celui de nos lointains ancêtres. Évelyne Heyer, biologiste française, professeure en génétique des populations, dévoile un récit de l'aventure humaine dans un style clair et accessible.

In 2018, the first genetically modified babies were reportedly born in China, made possible by the invention of CRISPR technology in 2012. This controversial advancement overturned the preexisting moral consensus, which had held for over 50 years before: While gene editing an adult person was morally acceptable, modifying babies, and thus subsequent generations, crossed a significant moral line. John H. Evans here provides a meta-level guide to how these debates move forward and their significance to society.