From the Battery to the Bronx, Manhattan is crawling with Vampyres. Joe Pitt is one of them, and he's not happy about it. Yeah, he gets to be tough as nails and hard to kill. But spending his nights trying to score a pint of blood to feed the Vyrus that's eating at him isn't his idea of a good time.
Now some fool who got himself infected with a flesh-eating bacteria is lurching around, trying to munch on folks' brains. Joe hates shamblers, but he's still the one who has to deal with them. It ain't easy going his own way, refusing to ally with the Clans that run the undead underside of Manhattan.
But it's worse once he gets mixed up with the Coalition and finds himself searching for a little rich girl who's gone missing. Now anarchist Vampyres are pushing him around, a crazy cult is stalking him, and Joe's got to find that girl and kill that shambler before the sun comes up.