エピソード

  • Sports Betting

    Sports Betting
    2026/01/06
    This week we talk about prediction markets, incentives, and gambling addiction.We also discuss insider trading, spot-fixing, and Gatorade.Recommended Book: The Kingdom, the Power, and the Glory by Tim AlbertaTranscriptPrediction markets are hundreds of years old, and have historically been used to determine the likelihood of something happening.In 1503, for instance, there was a market to determine who would become the next pope, and from the earliest days of commercial markets, there were associated prediction markets that were used to gauge how folks thought a given business would do during an upcoming economic quarter.The theory here is that while you can just ask people how well they think a political candidate will fare in an election or who they think will become the next pope, often their guesses, their assumptions, or their analysis will be swayed by things like political affiliation or maybe even what they think they’re meant to say—the popular papal candidate, for instance, or the non-obvious, asymmetric position on a big commercial enterprise that might help an analyst reinforce their brand as a contrarian.If you introduce money into the equation, though, forcing people to put down real currency on their suspicions and predictions, and give them the chance to earn money if they get things right, that will sometimes nudge these markets away from those other incentives, making the markets commercial enterprises of their own. It can shift the bias away from posturing and toward monetization, and that in turn, in theory at least, should make prediction markets more accurate because people will try to align themselves with the actual, real-deal outcome, rather than the popular—with their social tribe, at least—or compellingly unpopular view.This is the theory that underpins entities like Polymarket, Kalshi, Manifold Markets, and many other online prediction markets that have arisen over the past handful of years as regulations on these types of businesses have been eased, and as they’ve begun to establish themselves as credible players in the predicting-everything space.In politics in particular, these markets have semi-regularly shown themselves to be better gauges of who will actually win elections than conventional polls and surveys, and though their records are far from perfect and still heavily biased in some cases, such community-driven predictions from money-motivated markets are gaining credibility because of their capacity to incentivize people to put their money where their mouths are, and to try to profit from accurate preordination.The flip-side of these markets, and some might even say a built-in flaw with no obvious solution, is that they are rife with insider trading: people who are in the position to know things ahead of time making in some cases millions of dollars by placing big bets that, for them, aren’t bets at all, because they know what will or what is likely to happen.This seems to have occurred at least a few times with big political events in 2025, and it’s anticipated that it could become an even bigger issue in the future, especially for markets that use cryptocurrencies to manage payments, as those are even less likely than their fiat currency peers to keeps solid tabs on who’s actually behind these bets, and thus who might be trading on knowledge that they’re not supposed to be trading on.That said, it could be argued that such insider trading makes these markets even more accurate, eventually at least. And that points us toward another problem: the possibility that someone on the inside might look at a market and realize they can make a killing if they use their position, their power to sway these markets after placing a bet, giving them the ability to assure a payout by abusing their position—major events being influenced by the possibility of a community-funded payday for those in control.What I’d like to talk about today is the same general principle as it’s playing out in the sports world, and why the huge sums of money that are now sloshing around in the sports betting industry in the US are beginning to worry basically everyone, except the sports betting companies themselves.—In October of 2025, the head coach of the NBA basketball team, the Portland Trail Blazers, Chauncey Billups, Miami Heat player Terry Rozier, and former NBA player Damon Jones, and about 30 other people were arrested by the FBI due to their alleged illegal sports gambling activities. Rozier was already under investigation following unusual betting activity that was linked to his performance in a 2023 game—he was later cleared of wrongdoing, but the implication then and in this more recent instance is that he and those other folks who were rounded up by the FBI may have been involved in rigging things so they could get a big payoff on gambling markets.Similar things have been happening across the sports world, including a lifetime ban for Jontay Porter, a former ...
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    16 分
  • Data Center Politics

    Data Center Politics
    2025/12/23
    This week we talk about energy consumption, pollution, and bipartisan issues.We also discuss local politics, data center costs, and the Magnificent 7 tech companies.Recommended Book: Against the Machine by Paul KingsnorthTranscriptIn 2024, the International Energy Agency estimated that data centers consumed about 1.5% of all electricity generated, globally, that year. It went on to project that energy consumption by data centers could double by 2030, though other estimates are higher, due to the ballooning of investment in AI-focused data centers by some of the world’s largest tech companies.There are all sorts of data centers that serve all kinds of purposes, and they’ve been around since the mid-20th century, since the development of general purposes digital computers, like the 1945 Electronic Numerical Integrator and Computer, or ENIAC, which was programmable and reprogrammable, and used to study, among other things, the feasibility of thermonuclear weapons.ENIAC was built on the campus of the University of Pennsylvania and cost just shy of $500,000, which in today’s money would be around $7 million. It was able to do calculators about a thousand times faster than other, electro-mechanical calculators that were available at the time, and was thus considered to be a pretty big deal, making some types of calculation that were previously not feasible, not only feasible, but casually accomplishable.This general model of building big-old computers at a center location was the way of things, on a practical level, until the dawn of personal computers in the 1980s. The mainframe-terminal setup that dominated until then necessitated that the huge, cumbersome computing hardware was all located in a big room somewhere, and then the terminal devices were points of access that allowed people to tap into those centralized resources.Microcomputers of the sort of a person might have in their home changed that dynamic, but the dawn of the internet reintroduced something similar, allowing folks to have a computer at home or at their desk, which has its own resources, but to then tap into other microcomputers, and to still other larger, more powerful computers across internet connections. Going on the web and visiting a website is basically just that: connecting to another computer somewhere, that distant device storing the website data on its hard drive and sending the results to your probably less-powerful device, at home or work.In the late-90s and early 2000s, this dynamic evolved still further, those far-off machines doing more and more heavy-lifting to create more and more sophisticated online experiences. This manifested as websites that were malleable and editable by the end-user—part of the so-called Web 2.0 experience, which allowed for comments and chat rooms and the uploading of images to those sites, based at those far off machines—and then as streaming video and music, and proto-versions of social networks became a thing, these channels connecting personal devices to more powerful, far-off devices needed more bandwidth, because more and more work was being done by those powerful, centrally located computers, so that the results could be distributed via the internet to all those personal computers and, increasingly, other devices like phones and tablets.Modern data centers do a lot of the same work as those earlier iterations, though increasingly they do a whole lot more heavy-lifting labor, as well. They’ve got hardware capable of, for instance, playing the most high-end video games at the highest settings, and then sending, frame by frame, the output of said video games to a weaker device, someone’s phone or comparably low-end computer, at home, allowing the user of those weaker devices to play those games, their keyboard or controller inputs sent to the data center fast enough that they can control what’s happening and see the result on their own screen in less than the blink of an eye.This is also what allows folks to store backups on cloud servers, big hard drives located in such facilities, and it’s what allows the current AI boom to function—all the expensive computers and their high-end chips located at enormous data centers with sophisticated cooling systems and high-throughput cables that allow folks around the world to tap into their AI models, interact with them, have them do heavy-lifting for them, and then those computers at these data centers send all that information back out into the world, to their devices, even if those devices are underpowered and could never do that same kind of work on their own.What I’d like to talk about today are data centers, the enormous boom in their construction, and how these things are becoming a surprise hot button political issue pretty much everywhere.—As of early 2024, the US was host to nearly 5,400 data centers sprawled across the country. That’s more than any other nation, and that number is growing quickly as those ...
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    17 分
  • Chip Exports

    Chip Exports
    2025/12/16
    This week we talk about NVIDIA, AI companies, and the US economy.We also discuss the US-China chip-gap, mixed-use technologies, and export bans.Recommended Book: Enshittification by Cory DoctorowTranscriptI’ve spoken about this a few times in recent months, but it’s worth rehashing real quick because this collection of stories and entities are so central to what’s happening across a lot of the global economy, and is also fundamental, in a very load-bearing way, to the US economy right now.As of November of 2025, around the same time that Nvidia, the maker of the world’s best AI-optimized chips at the moment became the world’s first company to achieve a $5 trillion market cap, the top seven highest-valued tech companies, including Nvidia, accounted for about 32% of the total value of the US stock market.That’s an absolutely astonishing figure, as while Nvidia, Apple, Microsoft, Alphabet, Amazon, Broadcom, and Meta all have a fairly diverse footprint even beyond their AI efforts, a lot of that value for all of them is predicated on expected future income; which is to say, their market caps, their value according to that measure, is determined not by their current assets and revenue, but by what investors think or hope they’ll pull in and be worth in the future.That’s important to note because historically the sorts of companies that have market caps that are many multiples of their current, more concrete values are startups; companies in their hatchling phase that have a good idea and some kind of big potential, a big moat around what they’re offering or a blue ocean sub-industry with little competition in which they can flourish, and investment is thus expected to help them grow fast.These top seven tech companies, in contrast, are all very mature, have been around for a while and have a lot of infrastructure, employees, expenses, and all the other things we typically associated with mature businesses, not flashy startups with their best days hopefully ahead of them.Some analysts have posited that part of why these companies are pushing the AI thing so hard, and in particular pushing the idea that they’re headed toward some kind of generally useful AI, or AGI, or superhuman AI that can do everyone’s jobs better and cheaper than humans can do them, is that in doing so, they’re imagining a world in which they, and they alone, because of the costs associated with building the data centers required to train and run the best-quality AI right now, are capable of producing basically an economy’s-worth of AI systems and bots and machines operated by those AI systems.In other words, they’re creating, from whole cloth, an imagined scenario in which they’re not just worthy of startup-like valuations, worthy of market caps that are tens or hundreds of times their actual concrete value, because of those possible futures they’re imagining in public, but they’re the only companies worthy of those valuation multiples; the only companies that matter anymore.It’s likely that even if this is the case, that the folks in charge of these companies, and the investors who have money in them who are likely to profit when the companies grow and grow, actually do believe what they’re telling everyone about the possibilities inherent in building these sorts of systems.But there also seems to be a purely economic motive for exaggerating a lot and clearing out as much of the competition as possible as they grow bigger and bigger. Because maybe they’ll actually make what they’re saying they can make as a result of all that investment, that exuberance, but maybe, failing that, they’ll just be the last companies standing after the bubble bursts and an economic wildfire clears out all the smaller companies that couldn’t get the political relationships and sustaining cash they needed to survive the clear-out, if and when reality strikes and everyone realizes that sci-fi outcome isn’t gonna happen, or isn’t gonna happen any time soon.What I’d like to talk about today is a recent decision by the US government to allow Nvidia to sell some of its high-powered chips to China, and why that decision is being near-universally derided by those in the know.—In early December 2025, after a lot of back-and-forthing on the matter, President Trump announced that the US government will allow Nvidia, which is a US-based company, to export its H200 processors to China. He also said that the US government will collect a 25% fee on these sales.The H200 is Nvidia’s second-best chip for AI purposes, and it’s about six-times as powerful as the H20, which is currently the most advanced Nvidia chip that’s been cleared for sale to China. The Blackwell chip that is currently Nvidia’s most powerful AI offering is about 1.5-times faster than the H200 for training purposes, and five-times faster for AI inferencing, which is what they’re used for after a model is trained, and then it’s used for ...
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    14 分
  • Digital Asset Markets

    Digital Asset Markets
    2025/12/09
    This week we talk about in-game skins, investment portfolios, and Counter-Strike 2.We also discuss ebooks, Steam, and digital licenses.Recommended Book: Apple in China by Patrick McGeeTranscriptAlmost always, if you buy an ebook or game or movie or music album online, you’re not buying that ebook, or that game, or whatever else—you’re buying a license that allows you access it, often on a specified device or in a specified way, and almost always in a non-transferrable, non-permanent manner.This distinction doesn’t matter much to most of us most of the time. If I buy an ebook, chances are I just want to read that ebook on the device I used to buy it, or the kindle attached to my Amazon or other digital book service account. So I buy the book, read it on my ebook reader or phone, and that’s that; same general experience I would have with a paperback or hardback book.This difference becomes more evident when you think about what happens to the book after you read it, though. If I own a hard-copy, physical book, I can resell it. I can donate it. I can put it in a Little Free Library somewhere in my neighborhood, or give it to a friend who I think will enjoy it. I can pick it up off my shelf later and read the exact same book I read years before. Via whichever mechanism I choose, I’m either holding onto that exact book for later, or I’m transferring ownership of that book, that artifact that contains words and/or images that can now be used, read, whatever by that second owner. And they can go on to do the same: handing it off to a friend, selling it on ebay, or putting it on a shelf for later reference.Often the convenience and immediacy of electronic books makes this distinction a non-issue for those who enjoy them. I can buy an ebook from Amazon or Bookshop.org and that thing is on my device within seconds, giving me access to the story or information that’s the main, valuable component of a book for most of us, without any delay, without having to drive to a bookstore or wait for it to arrive in the mail. That’s a pretty compelling offer.This distinction becomes more pressing, however, if I decide I want to go back and read an ebook I bought years ago, later, only to find that the license has changed and maybe that book is no longer accessible via the marketplace where I purchased it. If that happens, I no longer have access to the book, and there’s no recourse for this absence—I agreed to this possibility when I “bought” the book, based on the user agreement I clicked ‘OK’ or ‘I agree’ on when I signed up for Amazon or whichever service I paid for that book-access.It also becomes more pressing if, as has happened many times over the past few decades, the publisher or some other entity with control over these book assets decides to change them.A few years ago, for instance, British versions of Roald Dalh’s ‘Matilda’ were edited to remove references to Joseph Conrad, who has in recent times been criticized for his antisemitism and racist themes in his writing. Some of RL Stine’s Goosebumps books were edited to remove references to crushes schoolgirls had on their headmaster, and descriptions of an overweight character that were, in retrospect, determined to be offensive. And various racial and ethnic slurs were edited out of some of Agatha Christie’s works around the same time.Almost always, these changes aren’t announced by the publishers who own the rights to these books, and they’re typically only discovered by eagle-eyed readers who note that, for instance, the publishers decided to change the time period in which something occurred, which apparently happened in one of Stine’s works, without obvious purpose. This also frequently happens without the author being notified, as was the case with Stine and the edits made to his books. The publishers themselves, when asked directly about these changes, often remain silent on the matter.What I’d like to talk about today is another angle of this distinction between physically owned media and digital, licensed versions of the same, and the at times large sums of money that can be gained or lost based on the decisions of the companies that control these licensed assets.—Counter-Strike 2 is a first-person shooter game that’s free-to-play, was released in 2023, and was developed by a company called Valve.Valve has developed all sorts of games over the years, including the Counter-Strike, Half-Life, DOTA, and Portal games, but they’re probably best known for their Steam software distribution platform.Steam allows customers to buy all sorts of software, but mostly games through an interface that also provides chat services and community forums. But the primary utility of this platform is that it’s a marketplace for buying and selling games, and it has match-making features for online multiplayer games, serves as a sort of library for gamers, so all their games are launchable from one place, and it serves ...
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    14 分
  • Climate Risk

    Climate Risk
    2025/12/02
    This week we talk about floods, wildfires, and reinsurance companies.We also discuss the COP meetings, government capture, and air pollution.Recommended Book: If Anyone Builds It, Everyone Dies by Eliezer Yudkowsky and Nate Soares TranscriptThe urban area that contains India’s capital city, New Delhi, called the National Capital Territory of Delhi, has a population of around 34.7 million people. That makes it the most populous city in the country, and one of the most populous cities in the world.Despite the many leaps India has made over the past few decades, in terms of economic growth and overall quality of life for residents, New Delhi continues to have absolutely abysmal air quality—experts at India’s top research hospital have called New Delhi’s air “severe and life-threatening,” and the level of toxic pollutants in the air, from cars and factories and from the crop-waste burning conducted by nearby farmers, can reach 20-times the recommended level for safe breathing.In mid-November 2025, the problem became so bad that the government told half its workers to work from home, because of the dangers represented by the air, and in the hope that doing so would remove some of the cars on the road and, thus, some of the pollution being generated in the area.Trucks spraying mist, using what are called anti-smog guns, along busy roads and pedestrian centers help—the mist keeping some of the pollution from cars from billowing into the air and becoming part of the regional problem, rather than an ultra-localized one, and pushing the pollutants that would otherwise get into people’s lungs down to the ground—though the use of these mist-sprayers has been controversial, as there are accusations that they’re primarily deployed near air-quality monitoring stations, and that those in charge put them there to make it seem like the overall air-quality is lower than it is, manipulating the stats so that their failure to improve practical air-quality isn’t as evident.And in other regional news, just southeast across the Bay of Bengal, the Indonesian government, as of the day I’m recording this, is searching for the hundreds of people who are still missing following a period of unusually heavy rains. These rains have sparked floods and triggered mudslides that have blocked roads, damaged bridges, and forced the evacuation of entire villages. More than 300,000 people have been evacuated as of last weekend, and more rain is forecast for the coming days.The death toll of this round of heavy rainfall—the heaviest in the region in years—has already surpassed 440 people in Indonesia, with another 160 and 90 in Thailand and Vietnam, respectively, being reported by those countries’ governments, from the same weather system.In Thailand, more than two million people were displaced by flooding, and the government had to deploy military assets, including helicopters launched from an aircraft carrier, to help rescue people from the roofs of buildings across nine provinces.In neighboring Malaysia, tens of thousands of people were forced into shelters as the same storm system barreled through, and Sri Lanka was hit with a cyclone that left at least 193 dead and more than 200 missing, marking one of the country’s worst weather disasters in recent years.What I’d like to talk about today is the climatic moment we’re at, as weather patterns change and in many cases, amplify, and how these sorts of extreme disasters are also causing untold, less reported upon but perhaps even more vital, for future policy shifts, at least, economic impacts.—The UN Conference of the Parties, or COP meetings, are high-level climate change conferences that have typically been attended by representatives from most governments each year, and where these representatives angle for various climate-related rules and policies, while also bragging about individual nations’ climate-related accomplishments.In recent years, such policies have been less ambitious than in previous ones, in part because the initial surge of interest in preventing a 1.5 degrees C increase in average global temperatures is almost certainly no longer an option; climate models were somewhat accurate, but as with many things climate-related, seem to have actually been a little too optimistic—things got worse faster than anticipated, and now the general consensus is that we’ll continue to shoot past 1.5 degrees C over the baseline level semi-regularly, and within a few years or a decade, that’ll become our new normal.The ambition of the 2015 Paris Agreement is thus no longer an option. We don’t yet have a new, generally acceptable—by all those governments and their respective interests—rallying cry, and one of the world’s biggest emitters, the United States, is more or less absent at new climate-related meetings, except to periodically show up and lobby for lower renewables goals and an increase in subsidies for and policies that favor the ...
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    16 分
  • Thorium Reactors

    Thorium Reactors
    2025/11/25
    This week we talk about radioactive waste, neutrons, and burn while breeding cycles.We also discuss dry casks, radioactive decay, and uranium.Recommended Book: Breakneck by Dan WangTranscriptRadioactive waste, often called nuclear waste, typically falls into one of three categories: low-level waste that contains a small amount of radioactivity that will last a very short time—this is stuff like clothes or tools or rags that have been contaminated—intermediate-level waste, which has been contaminated enough that it requires shielding, and high-level waste, which is very radioactive material that creates a bunch of heat because of all the radioactive decay, so it requires both shield and cooling.Some types of radioactive waste, particularly spent fuel of the kind used in nuclear power plants, can be reprocessed, which means separating it into other types of useful products, including another type of mixed nuclear fuel that can be used in lieu of uranium, though generally not economically unless uranium supplies are low. About a third of all spent nuclear fuel has already been reprocessed in some way.About 4% of even the recyclable stuff, though, doesn’t have that kind of second-life purpose, and that, combined with the medium- and long-lived waste that is quite dangerous to have just sitting around, has to be stored somehow, shielded and maybe cooled, and in some cases for a very long time: some especially long-lived fission products have half-lives that stretch into the hundreds of thousands or millions of years, which means they will be radioactive deep into the future, many times longer than humans have existed as a species.According to the International Atomic Energy Agency, something like 490,000 metric tons of radioactive spent fuel is currently being stored, on a temporary basis, at hundreds of specialized sites around the world. The majority of this radioactive waste is stored in pools of spent fuel water, cooled in that water somewhere near the nuclear reactors where the waste originated. Other waste has been relocated into what’re called dry casks, which are big, barrel-like containers made of several layers of steel, concrete, and other materials, which surround a canister that holds the waste, and the canister is itself surrounded by inert gas. These casks hold and cool waste using natural air convection, so they don’t require any kind of external power or water sources, while other solutions, including storage in water, sometimes does—and often the fuel is initially stored in pools, and is then moved to casks for longer-term storage.Most of the radioactive waste produced today comes in the form of spend fuel from nuclear reactors, which are typically small ceramic pellets made of low-enriched uranium oxide. These pellets are stacked on top of each other and encased in metal, and that creates what’s called a fuel rod.In the US, alone, about 2,000 metric tons of spent nuclear fuel is created each year, which is just shy of half an olympic sized swimming pool in terms of volume, and in many countries, the non-reuseable stuff is eventually buried, near the surface for the low- to intermediate-level waste, and deeper for high-level waste—deeper, in this context, meaning something like 200-1000 m, which is about 650-3300 feet, beneath the surface.The goal of such burying is to prevent potential leakage that might impact life on the surface, while also taking advantage of the inherent stability and cooler nature of underground spaces which are chosen for their isolation, natural barriers, and water impermeability, and which are also often reinforced with human-made supports and security, blocking everything off and protecting the surrounding area so nothing will access these spaces far into the future, and so that they won’t be broken open by future glaciation or other large-scale impacts, either.What I’d like to talk about today is another potential use and way of dealing with this type of waste, and why a recent, related development in China is being heralded as such a big deal.—An experimental nuclear reactor was built in the Gobi Desert by the Chinese Academy of Sciences Shanghai Institute of Applied Physics, and back in 2023 the group achieved its first criticality, got started up, basically, and it has been generating heat through nuclear fission ever since.What that means is that the nuclear reactor did what a nuclear reactor is supposed to do. Most such reactors exist to generate heat, which then creates steam and spins turbines, which generates electricity.What’s special about this reactor, though, is that it is a thorium molten salt reactor, which means it uses thorium instead of uranium as a fuel source, and the thorium is processed into uranium as part of the energy-making process, because thorium only contains trace amounts of fissile material, which isn’t enough to get a power-generating, nuclear chain reaction going.This reactor was able to successfully ...
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    13 分
  • Extrajudicial Killing

    Extrajudicial Killing
    2025/11/18
    This week we talk about Venezuela, casus belli, and drug smuggling.We also discuss oil reserves, Maduro, and Machado.Recommended Book: Dungeon Crawler Carl by Matt DinnimanTranscriptVenezuela, which suffered all sorts of political and economic crises under former president Hugo Chávez, has suffered even more of the same, and on a more dramatic scale, under Chávez’s successor, Nicolás Maduro.Both Chávez and Maduro have ruled over autocratic regimes, turning ostensibly democratic Venezuelan governments into governments ruled by a single person, and those they like and empower and reward, over time removing anyone from power who might challenge them, and collapsing all checks and balances within the structure of their government.They still hold elections, then, but like in Russia, the voting is just for show, the outcome predetermined, and anyone who gets too popular and who isn’t favored by the existing regime is jailed or killed or otherwise neutralized; the votes are then adjusted when necessary to make it look like the regime is still popular, and anyone who challenges that seeming popularity is likewise taken care of.As a result of that state of affairs, an unpopular regime with absolute power running things into the ground over the course of two autocrats’ administrations, Venezuela has suffered immense hyperinflation, high levels of crime and widespread disease, ever-increasing mortality rates, and even starvation, as fundamentals like food periodically become scarce. This has led to a swell of emigration out of the country, which has, during the past decade, become the largest ever recorded refugee crisis in the Americas, those who leave mostly flooding into neighboring countries like Colombia, Peru, and Ecuador.As of 2025, it’s estimated that nearly 8 million people, more than 20% of Venezuela’s entire population as of 2017, has fled the country to get away from the government, its policies, its collapsed economy, and the cultural homogeny that has led to so much crime, conflict, and oppression of those not favored by the people in charge.This has also led to some Venezuelans trying to get into the US, which was part of the justification for a proposed invasion of the country, by the US government, under the first Trump administration in 2017.The idea was that this is a corrupt, weak government that also happens to possess the largest proven oil reserves in the world. Its production of oil has collapsed along with everything else, in part because the government is so ineffectual, and in part because of outside forces, like longstanding sanctions by the US, which makes selling and profiting from said oil on the global market difficult.Apparently, though, Trump also just liked the idea of invading Venezuela through US ally Colombia, saying—according to Trump’s National Security advisor at the time, John Bolton—that Venezuela is really part of the US, so it would be “cool” for the US to take it. Trump also later said, in 2023, that when he left office Venezuela was about to collapse, and that he would have taken it over if he had been reelected instead of losing to Joe Biden, and the US would have then kept all the country’s oil.So there’s long been a seeming desire by Trump to invade Venezuela, partly on vibe grounds, the state being weak and why shouldn’t we own it, that kind of thing? But underlying that is the notion of the US being a country that can stomp into weaker countries, take their oil, and then nation-build, similar to what the government seemed to be trying to do when it invaded Iraq in the early 2000s, using 9/11 as a casus belli, an excuse to go to war, with an uninvolved nation that happened to own a bunch of oil resources the US government wanted for itself.What I’d like to talk about today is the seeming resurgence of that narrative, but this time with an, actual tangible reason to believe an invasion of Venezuela might occur sometime soon.—As I mentioned, though previously kind of a success story in South America, bringing people in from all over the continent and the world, Venezuela has substantially weakened under its two recent autocratic leaders, who have rebuilt everything in their image, and made corruption and self-serving the main driver behind their decisions for the direction of the country.A very popular candidate, María Corina Machado, was barred from participating in the country’s 2024 election, the country’s Supreme Court ruling that a 15-year ban on her holding public office because of her involvement with an alleged plot against Maduro with a previous candidate for office, Juan Guaido; Guiado is now in exile, run out of the country for winning an election against Maduro, which Maduro’s government has claimed wasn’t legit, but which dozens of governments recognize as having been legitimate, despite Maduro’s clinging to power after losing.So Machado is accused of being corrupt by Maduro’s corrupt government, and thus ...
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    15 分
  • Nitazenes

    Nitazenes
    2025/11/11
    This week we talk about OxyContin, opium, and the British East India Company.We also discuss isotonitazene, fentanyl, and Perdue.Recommended Book: The Thinking Machine by Stephen WittTranscriptOpioids have been used as painkillers by humans since at least the Neolithic period; there’s evidence that people living in the Iberian and Italian Peninsulas kept opium poppy seeds with them, and there’s even more evidence that the Ancient Greeks were big fans of opium, using it to treat pain and as a sleep aid.Opium was the only available opioid for most of human history, and it was almost always considered to be a net-positive, despite its downsides. It was incorporated into a mixture called laudanum, which was a blend of opium and alcohol, in the 17th century, and that helped it spread globally as Europeans spread globally, though it was also in use locally, elsewhere, especially in regions where the opium poppy grew naturally.In India, for instance, opium was grown and often used for its painkilling properties, but when the British East India Company took over, they decided to double-down on the substance as a product they could monopolize and grow into a globe-spanning enterprise.They went to great lengths to expand production and prevent the rise of potential competitors, in India and elsewhere, and they created new markets for opium in China by forcing the product onto Chinese markets, initially via smuggling, and then eventually, after fighting a series of wars focused on whether or not the British should be allowed to sell opium on the Chinese market, the British defeated the Chinese. And among other severely unbalanced new treaties, including the ceding of the Kowloon peninsula to the British as part of Hong Kong, which they controlled as a trading port, and the legalization of Christians coming into the country, proselytizing, and owning property, the Chinese were forced to accept the opium trade. This led to generations of addicts, even more so than before, when opium was available only illicitly, and it became a major bone of contention between the two countries, and informed China’s relationship with the world in general, especially other Europeans and the US, moving forward.A little bit later, in the early 1800s, a German pharmacist was able to isolate a substance called morphine from opium. He published a paper on this process in 1817, and in addition to this being the first alkaloid, the first organic compound of this kind to be isolated from a medicinal plant, which was a milestone in the development of modern drug discovery, it also marked the arrival of a new seeming wonder drug, that could ease pain, but also help control cold-related symptoms like coughing and gut issues, like diarrhea. Like many such substances back in the day, it was also often used to treat women who were demonstrating ‘nervous character,’ which was code for ‘behaving in ways men didn’t like or understand.’Initially, it was thought that, unlike with opium, morphine wasn’t addictive. And this thinking was premised on the novel application method often used for morphine, the hypermedia needle, which arrived a half-century after that early 1800s isolation of morphine from opium, but which became a major driver of the new drug’s success and utility. Such drugs, derived scientifically rather than just processing a plant, could be administered at specific, controllable doses. So surely, it was thought, this would alleviate those pesky addictive symptoms that many people experienced when using opioids in a more natural, less science-y way.That, of course, turned out not to be the case. But it didn’t stop the progression of this drug type, and the further development of more derivations of it, including powerful synthetic opioids, which first hit the scene in the mid-20th century.What I’d like to talk about today is the recent wave of opioid addictions, especially but not exclusively in the US, and the newest concern in this space, which is massively more powerful than anything that’s come before.—As I mentioned, there have been surges in opioid use, latent and externally forced, throughout modern human history.The Chinese saw an intense wave of opioid addiction after the British forced opium onto their markets, to the point that there was a commonly held belief that the British were trying to overthrow and enslave the Chinese by weighing them down with so many addicts who were incapable of doing much of anything; which, while not backed by the documentation we have from the era—it seems like they were just chasing profits—is not impossible, given what the Brits were up to around the world at that point in history.That said, there was a huge influx in opioid use in the late-1980s, when a US-based company called Purdue Pharma began producing and pushing a time-released opioid medication, which really hit the big-time in 1995, when they released a version of the drug called OxyContin.OxyContin ...
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