We’ve all heard the phrase “The mitochondria is the powerhouse of the cell” — probably in high school biology, on a meme, or even on a T-shirt. But what most people don’t realize is that this isn’t just trivia. This is the foundation of how you age, how you feel, and how your body performs every single day.

In this episode, Joanne breaks down what cellular health really means — in plain English — and why the slow changes we call “aging” actually begin at the cellular level. You’ll learn how the tiny factories inside your body, your mitochondria, determine your energy, recovery, fat-burning ability, and even how fast you age.

Aging doesn’t start on the outside — it starts inside your cells. As mitochondria (your body’s energy factories) become less efficient, you experience fatigue, slower recovery, brain fog, and stubborn fat gain. Cellular decline is aging.

Every cell in your body relies on mitochondria to create ATP — your body’s version of a rechargeable battery. That means every blink, every heartbeat, every lift in the gym depends on these little energy makers. When they’re working well, you feel strong and unstoppable. When they’re not, you feel sluggish, no matter how “healthy” you think you are.

Healthy mitochondria can switch easily between using carbs and fats for fuel — what’s called metabolic flexibility. When that flexibility is lost, you become dependent on sugar and frequent snacks to keep going. That “I can’t skip breakfast or I’ll crash” feeling? It’s not lack of willpower — it’s your mitochondria waving the white flag.

When you constantly overfeed your cells — too much sugar, processed fat, or just too much food — mitochondria can’t keep up. They start producing “smoke” in the form of free radicals. Over time, this creates oxidative stress, damaging your proteins, membranes, and DNA. It’s the invisible corrosion that accelerates aging.

While some mitochondrial decline happens naturally with age, most of it comes from modern living — poor sleep, chronic stress, processed food, alcohol, and inactivity. These don’t just make you tired; they literally wear down your cells. The good news? The opposite is true too. You can rebuild cellular strength through simple, repeatable habits that compound over time.

Your body can make new mitochondria — a process called mitochondrial biogenesis. Exercise (especially Zone 2 cardio), consistent sleep, balanced nutrition, and hormetic stressors (like cold exposure or fasting) signal your body to “hire new workers.” More mitochondria = more energy, better fat burning, and slower aging.

• Prioritize daily movement — especially steady-state cardio.

• Eat nutrient-dense foods and avoid constant grazing.

• Get consistent, high-quality sleep.

• Expose your body to small challenges: sauna, cold plunges, fasting.

• Reduce alcohol, smoking, and ultra-processed food.

• Think energy first, not calories first.

You can’t see your mitochondria, but you can feel them. When they’re healthy, you have energy, focus, resilience, and a body that responds. When they’re not, you feel old — even if you’re not.

The real secret to longevity and vitality isn’t a magic supplement or a fancy detox. It’s cellular health. It’s the simple lifestyle habits — the ones we brush off as “too small to matter” — that quietly build your cellular foundation over time.

🎧 Tune in and learn how to become the CEO of your own cellular factory. Because when your cells thrive, you thrive.

🔗 Learn more at www.midlifemonth.com 🔗 Explore coaching and programs at www.jlcstrong.com

Why the FDA Reclassified 17 Peptides — and What It Really Means”

The headlines said the FDA “banned 17 peptides.” But the truth? It’s not a sudden ban — it’s the inevitable fallout of peptides becoming too popular for their own good.

In this episode, Joanne Lee Cornish breaks down what really happened in July, why it started with the GLP-1 explosion, and how the FDA’s new classification is reshaping the peptide world. From BPC-157 to MOTs-C and Epitalon, we’ll explore what each of the 17 peptides was known for, why compounding pharmacies can’t touch them anymore, and why large-scale human trials are still a distant dream.

Joanne also dives into the biggest roadblocks — why most peptides can’t be patented, and why that makes them a direct threat to multi-billion-dollar pharmaceuticals. The result? They’re too natural to own, too effective to ignore, and too competitive for Big Pharma to tolerate.

If you’re curious about where the peptide world stands now — what’s still available, what to be cautious about, and how this all ties back to the booming GLP-1 market — this 20-minute episode will bring it all together.

• What really happened in July: the FDA’s reclassification of 17 peptides

• Why GLP-1 drugs like semaglutide and tirzepatide triggered the crackdown

• A simple breakdown of what each peptide is used for — from gut repair to muscle growth

• How the FDA’s approval process really works (and why it costs millions)

• The two biggest barriers to legitimizing peptides: 1️⃣ You can’t patent what nature already makes 2️⃣ They compete directly with blockbuster drugs

• Why Big Pharma has zero incentive to fund peptide trials

• The gray zone: peptides still available through research labs — and how to approach them cautiously

Peptides didn’t suddenly become unsafe — they became too popular. And when something natural threatens a billion-dollar industry, regulation always follows.

Learn more about the peptides discussed in this episode and the science behind them:

• 5-Amino-1MQ – a breakthrough compound supporting muscle preservation and metabolic health: www.5amino.com

• SLU-PP-332 – designed to enhance cellular energy and performance: www.slu332.com

🎙️ Midlife Mayhem is available on all major platforms. Subscribe, share, and leave a review if you enjoyed this deep dive into the science, politics, and reality of modern health optimization.