『Midlife Mayhem』のカバーアート

Midlife Mayhem

Midlife Mayhem

著者： joanne lee cornish
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 Welcome to Midlife Mayhem, where we embark on an empowering journey through the world of midlife body composition transformation. In this space, we challenge the misconceptions surrounding aging and redefine what’s possible for those navigating the exhilarating terrain of midlife and beyond. Join me as we explore the science, mindset shifts, and practical strategies that can help you sculpt the body of your dreams, proving that age is no barrier to achieving peak vitality and confidence. Whether you’re seeking to shed excess weight, gain lean muscle, or simply feel more vibrant, this podcast is your trusted companion in the pursuit of a healthier, stronger, and more resilient you. Welcome to a new era of limitless possibilities in midlife body transformation. ”Hi I’m Joanne, and I have been coaching body composition for over 30 years. I’ve worked with household names that you know, and I have worked with thousands of people in my group coaching programs. I was a pro bodybuilder in the 90’s with a top 10 physique in the world, but I only knew how to be in shape and out of shape. That frustration led me on a fascinating path of self-study where I found all the answers I could have asked for and more. But I had to dig for the answers, and I have my own ideas on why those answers are not mainstream and why the weight loss industry fails you, but I will save that for a Midlife Mayhem episode. Author of ”When Calories & Cardio Don’t Cut It”New podcast weblogCopyright 2023 All rights reserved. エクササイズ・フィットネス フィットネス・食生活・栄養 個人的成功 自己啓発 衛生・健康的な生活
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  • Birth Control ≠ HRT, so why do they prescribe it?

    Birth Control ≠ HRT, so why do they prescribe it?
    2025/09/15

    Episode Title: Why the WHI Study Still Misguides Midlife Women + Why Birth Control Isn’t Hormone Therapy

    Episode Overview

    Mastering Midlife starts on SUNDAY (Sept 21) www.midlifemonth.com

    In this episode of Midlife Mayhem, Joanne Lee Cornish breaks down one of the most damaging studies in women’s health history—the Women’s Health Initiative (WHI)—and explains how its flawed design still shapes the way doctors approach hormone replacement therapy (HRT) today.

    She also explores why so many women in their 40s and 50s are prescribed birth control as “hormone therapy”, why it might feel like it works, and why the long-term consequences can be deeply concerning.

    This conversation is not just for women—men face their own version of hormonal decline in midlife, and understanding both journeys creates stronger health, stronger relationships, and a deeper level of compassion.

    What You’ll Learn in This Episode

    • The WHI Study: What Went Wrong

      • Conducted in the 1990s, cost nearly $1 billion, involved 160,000 women.

      • The average participant age was 63—decades older than the women HRT was meant to study.

      • Participants were often overweight, hypertensive, or smokers—factors that skewed results.

      • The hormones tested (Premarin + Provera) were outdated, synthetic formulations rarely used today.

    • Relative Risk vs Absolute Risk: How the Media Got It Wrong

      • Headlines screamed “26% increase in breast cancer risk.”

      • Actual increase was from 3 in 1,000 women to 3.8 in 1,000.

      • A frightening relative risk became a misleading headline that terrified women and doctors, leading to decades of confusion and reluctance to prescribe HRT.

    • The Fallout That Still Shapes Midlife Care Today

      • Doctors stopped prescribing HRT.

      • A generation of physicians received little-to-no training in modern, bioidentical hormone therapy.

      • Millions of women were left without proper guidance during midlife.

    • Birth Control as HRT: Why It’s Not the Same

      • Birth control suppresses natural hormone production instead of replacing what’s missing.

      • It significantly lowers testosterone—a key hormone for energy, mood, libido, and muscle tone.

      • Higher risks of clots and stroke, especially in women over 35, smokers, or those with metabolic issues.

      • Doctors prescribe it out of familiarity, insurance coverage, and convenience—not because it’s the best solution.

    • Why Testosterone Matters in Midlife Women

      • Already declining naturally, testosterone is further suppressed by birth control.

      • Leads to reduced strength, energy, motivation, and intimacy.

      • Many women don’t connect these struggles back to suppressed testosterone until years later.

    • Men and Midlife: The Overlooked Journey

      • Women’s hormonal chaos hits in their 40s, men’s decline (andropause) often creeps in during their 50s.

      • The mismatch in timing creates tension, frustration, and distance in relationships.

      • Understanding each other’s hormonal journeys builds patience, compassion, and stronger partnerships.

    Why This Matters

    We’ve spent over two decades living with the fallout of a flawed study. If you’ve been scared of HRT, or if your doctor avoids the conversation, this episode will help you understand why—and how to ask better questions, find the right practitioners, and take control of your midlife journey.

    Call to Action

    This episode is just the beginning. If you want to go deeper, get real strategies, and finally master your midlife years, join my Mastering Midlife Program—starting Sunday, September 21.

    👉 www.midlifemonth.com

    This program only runs once a year. You’ll get:

    • Live coaching calls (not a faceless webinar—you’ll be known by name)

    • Access to an exclusive content library

    • Practical, science-backed strategies for hormones, health, and body composition

    • A supportive group of like-minded men and women navigating midlife together

    As one past participant said:

    “I didn’t want to join. My wife dragged me in. But this program did more for our marriage than two years of therapy.”

    Don’t wait—this is your chance to stop guessing, stop Googling, and start thriving.

    ✨ Midlife may feel like mayhem, but with the right knowledge and strategy, it becomes the best chapter yet.
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    32 分
  • DHM + L-Cysteine & Alpha GPC + DLPA: Reduce Alcohol’s Effects and Unlock Laser Focus

    DHM + L-Cysteine & Alpha GPC + DLPA: Reduce Alcohol’s Effects and Unlock Laser Focus
    2025/09/10
    Welcome to Midlife Mayhem! For the first time, I’m not just talking to you through your headphones — I’m also filming this for YouTube. So if you’d rather see me chatting through today’s episode, head over to (joanne lee cornish) my YouTube channel. Today, I want to share some of the lesser-known supplement pairings I personally use and keep on hand. These aren’t your typical multivitamins or fish oils — they’re unique stacks that I pull out a couple of times a month when I need them. And since my Mastering Midlife Program kicks off on September 21, I thought this was the perfect time to give you a preview. 🍶 DHM + L-Cysteine: My “Alcohol Insurance” Stack Okay, let’s talk about what I jokingly call my going-out stack. If I know I’m going to enjoy a glass of wine or two, this is what I reach for: DHM (Dihydromyricetin): When you drink alcohol, your liver breaks it down in steps. First, ethanol (the alcohol in your drink) is broken down into acetaldehyde — and that’s the nasty stuff that makes you feel headachy, nauseous, and sluggish. Your body has an enzyme called acetaldehyde dehydrogenase, which converts that toxic acetaldehyde into harmless acetic acid (basically vinegar). The catch? Your liver can only work at a steady pace — it doesn’t speed up just because you had three margaritas. Research shows DHM can help upregulate acetaldehyde dehydrogenase, essentially nudging your body to clear out that toxic middle step faster. L-Cysteine: This one is an amino acid that helps your body make glutathione, your master antioxidant. Think of glutathione as your liver’s cleanup crew — it sweeps away leftover toxins and free radicals so you can recover more quickly. By taking L-Cysteine with DHM, you’re not only speeding up the breakdown of alcohol but also giving your body extra tools to handle the oxidative stress that comes with drinking. 💡 How I use it: If I know I’ll have more than one drink, I take one capsule of DHM (around 350–500 mg) and one capsule of L-Cysteine (500 mg) after my first drink. Honestly, if I only have one glass, I don’t need them, but I’ll often still take them — it just helps me feel clearer and better the next day. And here’s the kicker: these are simple, inexpensive supplements. The DHM I use is by Nutricost, and the L-Cysteine is by NOW — but you don’t have to stick to those brands. They’re basic compounds, no need to overpay for a fancy “hangover pill” when you can pair them yourself for less than $30 and get way more doses. ⚡️ Alpha GPC + DLPA: The Focus & Flow Stack Now, let’s shift gears to another duo I love — not for social nights out, but for when I need serious focus and mental clarity. This is my deep work stack, perfect for writing, planning, or any project that requires a lot of brainpower. DLPA (DL-Phenylalanine): This supplement is a blend of two mirror-image forms of the amino acid phenylalanine. The L-form is a precursor to dopamine — the neurotransmitter responsible for motivation, focus, and drive. Think of dopamine as the spark that helps you get things done. The D-form works differently: it helps slow the breakdown of endorphins, those natural “feel-good” chemicals your body releases when you laugh, exercise, or enjoy a great meal. By keeping your endorphins around longer, it helps sustain a positive, motivated state. Alpha GPC (L-alpha-glycerylphosphorylcholine): This is a highly bioavailable source of choline, which your brain uses to make acetylcholine — a neurotransmitter tied to learning, memory, and focus. Think of it as premium fuel for your brain’s communication system. When acetylcholine is abundant, neurons fire more efficiently, and everything feels clearer and sharper. 💡 How I use it: I don’t take these every day. For me, it’s more of a “power button” stack. If I know I need a solid 2–3 hours of uninterrupted writing, content creation, or really intense focus, I’ll take one DLPA and one Alpha GPC together. About 20–30 minutes later, it feels like the fog lifts, I’ve got more drive, and I can really lock in. Are they stimulants? Not in the jittery, wired way that coffee or pre-workouts can be. You don’t get the crash. Instead, it’s like your brain is clicking into gear — smooth energy, clearer thinking, better recall. 🧘 Mastering Midlife Program — Starts September 21! If all of this has your brain buzzing and you want to learn more about how to use supplements (without the confusion or hype), then I’d love to invite you to join me in the Mastering Midlife Program, starting September 21st. Here’s what you’ll get: 🔟 Live coaching calls over 6 weeks — each one covering a key pillar of thriving in midlife. 📚 A growing library of 70+ pieces of content — with strategies, deep dives, and explanations you can access for a full year. 🎯 My top 5 everyday supplements that I recommend for everyone, plus specialized ...
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    33 分
  • Cellular Energy, NAD+, and Gut Diversity Demystified

    Cellular Energy, NAD+, and Gut Diversity Demystified
    2025/09/08
    Recorded: September 6 (rainy morning in Idaho 🌧️) Host: Joanne Lee Cornish Theme: Cutting through the “too simple” and the “too complex” to the useful middle—so you actually know what to do and why it works. Why this episode matters There’s a giant gap in health education: on one side, fluffy tips (“eat healthy fats!”); on the other, firehose-science that sounds impressive but leaves you asking, …now what? This episode lives in the middle. You’ll get plain-English explanations of high-value concepts and, more importantly, how to implement them for midlife results. ⚡️ Heads up: Enrollment for Mastering Midlife starts really soon. It’s a 10-Step to Success program with live coaching plus a full content library so you can learn at your own pace. Details below. Episode Highlights 1) The “Gap” I Fill (00:29–03:31) The internet swings between oversimplified advice and overcomplicated biohacking. Most people don’t need more noise—they need actionable explanations and a clear progression. That’s why my programs are designed as a journey—not 10 random Zooms. 2) Why a Progressive Framework Works (03:01–04:46) Mastering Midlife follows a 10-step sequence across bloodwork, smart nutrition, supplements, exercise, and strength training. Each step builds on the last so you can understand, apply, and sustain. 3) Buzzwords You Hear Everywhere—Decoded (04:46–10:07) We name the elephant in the room: terms are tossed around like everyone learned this in school (we didn’t). This series clarifies the why and the how so you can use the info. Topics called out: mitochondria, cellular energy, NAD+, autophagy, mTOR/AMPK, BDNF, leptin resistance, metabolic flexibility, glycation, inflamaging, photobiomodulation, peptides (BPC-157, tesamorelin, GHK), exosomes, stem cells, senescent cells, HRV, cold exposure/brown fat, methylation, zonulin, LPS, histamine intolerance, oxalates, collagen cross-linking, microdosing, sarcopenia, longevity genes, and more. 4) Deep Dives (Plain English) A) Mitochondria & Cellular Energy (10:07–18:43) Mitochondria are more than “little batteries.” They decide: How efficiently you burn fat How much energy is available to brain/muscle/organs How quickly you age Cellular energy = ability to produce ATP (the “currency of life”). Low ATP → fatigue, cravings, slow recovery, poor gains. Support via quality food, smart meal timing (including some fasting), resistance training, sleep, and light (e.g., red light therapy). B) NAD+ & Why Everyone’s Talking About It (18:43–23:54) NAD+ is a coenzyme required to turn food into usable energy. Levels decline with age. You’ll hear about NR/NMN (precursors). Lifestyle also protects NAD (exercise, sleep, fasting). 5-Amino-1MQ (which I carry) supports your own NAD production. Warning: medications may create great scale changes, but cellular health still matters—don’t abandon the basics. C) Microbiome Diversity (24:19–29:49) Think of your gut like a rainforest—diversity = resilience. Diverse microbes = better digestion, vitamins, hormone balance, immune regulation, even mood/cognition (gut-brain axis). Midlife naturally reduces diversity. Counter it by: Eliminating ultra-processed foods (non-negotiable) Eating more fiber (feeds good bacteria) Including fermented foods (adds good bacteria) D) LPS & Leaky Gut—The Silent Saboteur (29:49–34:35) LPS (lipopolysaccharide) lives on certain gut bacteria. Fine inside the gut; toxic if it leaks out. With leaky gut, LPS escapes → big immune reaction → systemic inflammation, brain fog, joint pain, fatigue, insulin resistance, mood issues; linked with autoimmunity. Drivers: ultra-processed food, irritants, toxins, antibiotics, high sugar. I have a free leaky gut video—email me. E) Oxidative Stress (34:57–41:51) When cells make energy, free radicals (sparks) are created. Antioxidants are the cleanup crew. If sparks build up without cleanup, you get a fire = oxidative stress. Result: faster aging (wrinkles), joint issues, chronic disease risk, low energy. Fix the inputs: whole foods, consistent activity, sleep, stress management. As we age, internal antioxidant systems decline → diet quality matters more. 5) Big Picture (42:18–44:57) Weight alone isn’t the game. Cellular health is. When people understand the why, simple solutions are finally implemented—and they stick. 6) The Power of Community (45:20–46:34) Join as a front-row participant or low-key spectator; the group dynamic accelerates results. Coaching is not about dumping information—it’s progression + conversation. About the Program: Mastering Midlife — 10-Step to Success Starts soon (runs live once per year). 10 progressive steps that cover: bloodwork, smart nutrition, supplementation, strength training, recovery, metabolic health, gut health, and more. Live coaching calls + full content library (review at your pace all year)....
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    51 分
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