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  • DHM + L-Cysteine & Alpha GPC + DLPA: Reduce Alcohol’s Effects and Unlock Laser Focus

    DHM + L-Cysteine & Alpha GPC + DLPA: Reduce Alcohol’s Effects and Unlock Laser Focus
    2025/09/10
    Welcome to Midlife Mayhem! For the first time, I’m not just talking to you through your headphones — I’m also filming this for YouTube. So if you’d rather see me chatting through today’s episode, head over to (joanne lee cornish) my YouTube channel. Today, I want to share some of the lesser-known supplement pairings I personally use and keep on hand. These aren’t your typical multivitamins or fish oils — they’re unique stacks that I pull out a couple of times a month when I need them. And since my Mastering Midlife Program kicks off on September 21, I thought this was the perfect time to give you a preview. 🍶 DHM + L-Cysteine: My “Alcohol Insurance” Stack Okay, let’s talk about what I jokingly call my going-out stack. If I know I’m going to enjoy a glass of wine or two, this is what I reach for: DHM (Dihydromyricetin): When you drink alcohol, your liver breaks it down in steps. First, ethanol (the alcohol in your drink) is broken down into acetaldehyde — and that’s the nasty stuff that makes you feel headachy, nauseous, and sluggish. Your body has an enzyme called acetaldehyde dehydrogenase, which converts that toxic acetaldehyde into harmless acetic acid (basically vinegar). The catch? Your liver can only work at a steady pace — it doesn’t speed up just because you had three margaritas. Research shows DHM can help upregulate acetaldehyde dehydrogenase, essentially nudging your body to clear out that toxic middle step faster. L-Cysteine: This one is an amino acid that helps your body make glutathione, your master antioxidant. Think of glutathione as your liver’s cleanup crew — it sweeps away leftover toxins and free radicals so you can recover more quickly. By taking L-Cysteine with DHM, you’re not only speeding up the breakdown of alcohol but also giving your body extra tools to handle the oxidative stress that comes with drinking. 💡 How I use it: If I know I’ll have more than one drink, I take one capsule of DHM (around 350–500 mg) and one capsule of L-Cysteine (500 mg) after my first drink. Honestly, if I only have one glass, I don’t need them, but I’ll often still take them — it just helps me feel clearer and better the next day. And here’s the kicker: these are simple, inexpensive supplements. The DHM I use is by Nutricost, and the L-Cysteine is by NOW — but you don’t have to stick to those brands. They’re basic compounds, no need to overpay for a fancy “hangover pill” when you can pair them yourself for less than $30 and get way more doses. ⚡️ Alpha GPC + DLPA: The Focus & Flow Stack Now, let’s shift gears to another duo I love — not for social nights out, but for when I need serious focus and mental clarity. This is my deep work stack, perfect for writing, planning, or any project that requires a lot of brainpower. DLPA (DL-Phenylalanine): This supplement is a blend of two mirror-image forms of the amino acid phenylalanine. The L-form is a precursor to dopamine — the neurotransmitter responsible for motivation, focus, and drive. Think of dopamine as the spark that helps you get things done. The D-form works differently: it helps slow the breakdown of endorphins, those natural “feel-good” chemicals your body releases when you laugh, exercise, or enjoy a great meal. By keeping your endorphins around longer, it helps sustain a positive, motivated state. Alpha GPC (L-alpha-glycerylphosphorylcholine): This is a highly bioavailable source of choline, which your brain uses to make acetylcholine — a neurotransmitter tied to learning, memory, and focus. Think of it as premium fuel for your brain’s communication system. When acetylcholine is abundant, neurons fire more efficiently, and everything feels clearer and sharper. 💡 How I use it: I don’t take these every day. For me, it’s more of a “power button” stack. If I know I need a solid 2–3 hours of uninterrupted writing, content creation, or really intense focus, I’ll take one DLPA and one Alpha GPC together. About 20–30 minutes later, it feels like the fog lifts, I’ve got more drive, and I can really lock in. Are they stimulants? Not in the jittery, wired way that coffee or pre-workouts can be. You don’t get the crash. Instead, it’s like your brain is clicking into gear — smooth energy, clearer thinking, better recall. 🧘 Mastering Midlife Program — Starts September 21! If all of this has your brain buzzing and you want to learn more about how to use supplements (without the confusion or hype), then I’d love to invite you to join me in the Mastering Midlife Program, starting September 21st. Here’s what you’ll get: 🔟 Live coaching calls over 6 weeks — each one covering a key pillar of thriving in midlife. 📚 A growing library of 70+ pieces of content — with strategies, deep dives, and explanations you can access for a full year. 🎯 My top 5 everyday supplements that I recommend for everyone, plus specialized ...
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    33 分
  • Cellular Energy, NAD+, and Gut Diversity Demystified

    Cellular Energy, NAD+, and Gut Diversity Demystified
    2025/09/08
    Recorded: September 6 (rainy morning in Idaho 🌧️) Host: Joanne Lee Cornish Theme: Cutting through the “too simple” and the “too complex” to the useful middle—so you actually know what to do and why it works. Why this episode matters There’s a giant gap in health education: on one side, fluffy tips (“eat healthy fats!”); on the other, firehose-science that sounds impressive but leaves you asking, …now what? This episode lives in the middle. You’ll get plain-English explanations of high-value concepts and, more importantly, how to implement them for midlife results. ⚡️ Heads up: Enrollment for Mastering Midlife starts really soon. It’s a 10-Step to Success program with live coaching plus a full content library so you can learn at your own pace. Details below. Episode Highlights 1) The “Gap” I Fill (00:29–03:31) The internet swings between oversimplified advice and overcomplicated biohacking. Most people don’t need more noise—they need actionable explanations and a clear progression. That’s why my programs are designed as a journey—not 10 random Zooms. 2) Why a Progressive Framework Works (03:01–04:46) Mastering Midlife follows a 10-step sequence across bloodwork, smart nutrition, supplements, exercise, and strength training. Each step builds on the last so you can understand, apply, and sustain. 3) Buzzwords You Hear Everywhere—Decoded (04:46–10:07) We name the elephant in the room: terms are tossed around like everyone learned this in school (we didn’t). This series clarifies the why and the how so you can use the info. Topics called out: mitochondria, cellular energy, NAD+, autophagy, mTOR/AMPK, BDNF, leptin resistance, metabolic flexibility, glycation, inflamaging, photobiomodulation, peptides (BPC-157, tesamorelin, GHK), exosomes, stem cells, senescent cells, HRV, cold exposure/brown fat, methylation, zonulin, LPS, histamine intolerance, oxalates, collagen cross-linking, microdosing, sarcopenia, longevity genes, and more. 4) Deep Dives (Plain English) A) Mitochondria & Cellular Energy (10:07–18:43) Mitochondria are more than “little batteries.” They decide: How efficiently you burn fat How much energy is available to brain/muscle/organs How quickly you age Cellular energy = ability to produce ATP (the “currency of life”). Low ATP → fatigue, cravings, slow recovery, poor gains. Support via quality food, smart meal timing (including some fasting), resistance training, sleep, and light (e.g., red light therapy). B) NAD+ & Why Everyone’s Talking About It (18:43–23:54) NAD+ is a coenzyme required to turn food into usable energy. Levels decline with age. You’ll hear about NR/NMN (precursors). Lifestyle also protects NAD (exercise, sleep, fasting). 5-Amino-1MQ (which I carry) supports your own NAD production. Warning: medications may create great scale changes, but cellular health still matters—don’t abandon the basics. C) Microbiome Diversity (24:19–29:49) Think of your gut like a rainforest—diversity = resilience. Diverse microbes = better digestion, vitamins, hormone balance, immune regulation, even mood/cognition (gut-brain axis). Midlife naturally reduces diversity. Counter it by: Eliminating ultra-processed foods (non-negotiable) Eating more fiber (feeds good bacteria) Including fermented foods (adds good bacteria) D) LPS & Leaky Gut—The Silent Saboteur (29:49–34:35) LPS (lipopolysaccharide) lives on certain gut bacteria. Fine inside the gut; toxic if it leaks out. With leaky gut, LPS escapes → big immune reaction → systemic inflammation, brain fog, joint pain, fatigue, insulin resistance, mood issues; linked with autoimmunity. Drivers: ultra-processed food, irritants, toxins, antibiotics, high sugar. I have a free leaky gut video—email me. E) Oxidative Stress (34:57–41:51) When cells make energy, free radicals (sparks) are created. Antioxidants are the cleanup crew. If sparks build up without cleanup, you get a fire = oxidative stress. Result: faster aging (wrinkles), joint issues, chronic disease risk, low energy. Fix the inputs: whole foods, consistent activity, sleep, stress management. As we age, internal antioxidant systems decline → diet quality matters more. 5) Big Picture (42:18–44:57) Weight alone isn’t the game. Cellular health is. When people understand the why, simple solutions are finally implemented—and they stick. 6) The Power of Community (45:20–46:34) Join as a front-row participant or low-key spectator; the group dynamic accelerates results. Coaching is not about dumping information—it’s progression + conversation. About the Program: Mastering Midlife — 10-Step to Success Starts soon (runs live once per year). 10 progressive steps that cover: bloodwork, smart nutrition, supplementation, strength training, recovery, metabolic health, gut health, and more. Live coaching calls + full content library (review at your pace all year)....
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    51 分
  • The Dangerous Advice That’s Keeping Midlifers Weak

    The Dangerous Advice That’s Keeping Midlifers Weak
    2025/08/29
    Show Notes – Midlife Mayhem Podcast Episode Type: Venting / Educational Rant Program Mentioned: Mastering Midlife (Sept 21 – Nov 1) → www.midlifemonth.com 🎙️ Episode Overview In this episode, Joanne takes aim at a recent Telegraph article that claimed you can lose weight without losing muscle by following outdated and misleading advice. From the laughably low protein recommendations (45g/day for women) to the suggestion that light weights and bodyweight exercise are enough for midlife muscle preservation, Jo breaks down why this kind of misinformation is dangerous—not just frustrating. This episode is raw, fiery, and unapologetic—a venting session that highlights why midlife is not the time for “everyone gets a trophy” advice. Instead, it’s the time for clear, science-backed strategies that actually protect muscle, metabolism, and long-term vitality. 🔥 Key Topics Covered 1. Why 45g of Protein is a Joke The article recommended ~0.75 g/kg of protein per day (≈45g for women, 55g for men). Joanne explains why this 1960s RDA guideline is dangerously outdated and fails to account for modern research, especially in midlife when anabolic resistance sets in. For true muscle preservation, most adults need closer to 1.6–2.2 g/kg bodyweight. That’s triple what the article suggested. 2. Anabolic Resistance: The Silent Muscle Killer Jo breaks down the science of anabolic resistance and its connection to insulin resistance: Insulin resistance → harder to move glucose into muscle. Anabolic resistance → harder to move amino acids into muscle. Result: even if you think you’re eating enough protein, your muscles may not be getting fed. Why this matters: muscle loss accelerates with age, even for people who “do all the right things,” unless nutrition and training are dialed in. 3. The “Light Weights & Pilates” Trap The article claimed bodyweight training, yoga, Pilates, and light weights with high reps are “enough” for muscle preservation in midlife. Joanne explains why this is not effective for building or maintaining meaningful lean mass. Strength training needs progressive overload—challenging resistance that forces muscles to adapt. While bodyweight and Pilates have benefits, they don’t replace structured resistance training for midlife muscle protection. 4. Why This Matters Beyond Vanity Holding onto muscle isn’t about just looking “toned”—it’s about survival and independence later in life. Without enough muscle: Metabolism plummets. Fatigue and frailty increase. Quality of life in your 70s and 80s diminishes sharply. Midlife is the one opportunity to re-route the trajectory of aging—miss it, and the next chapter becomes exponentially harder. 5. The Problem With Mainstream Advice Articles like this reinforce mediocrity disguised as inclusivity: “everyone’s a winner” messaging. Jo argues this robs people of their chance to succeed because they’re never told the truth about what’s necessary. Clear, accurate information empowers people to do the work—and it doesn’t need to be complicated. It just needs to be correct. 6. Midlife as the Opportunity Window Too many people fear midlife without realizing the real fear should be what comes after if they don’t act now. Midlife = chance to reset metabolism, protect muscle, preserve energy, and ensure the later decades of life are vibrant. Ignore it, and the outcome is predictable: loss of muscle, independence, and quality of life. 💡 Cutting-Edge Add-Ons Protein Distribution Matters → It’s not just how much protein you eat, but how you spread it through the day (aim for 25–40g per meal with sufficient leucine). The Role of Resistance Training → Strength training triggers mTOR and muscle protein synthesis. Lighter loads can work only if trained to failure—but that’s rarely sustainable. Metabolic Flexibility → Without muscle, the body loses its best tool for glucose disposal and fat utilization, fueling insulin resistance. Hormonal Influence → Midlife shifts in estrogen, progesterone, and testosterone amplify anabolic resistance—making accurate protein and strength training strategies non-negotiable. 📢 Featured Program: Mastering Midlife Midlife doesn’t have to mean decline. Joanne’s signature Mastering Midlife program runs Sept 21 – Nov 1 and gives you the full roadmap for building muscle, balancing hormones, optimizing metabolism, and rewriting the script for your next decades. 👉 Learn more and join at www.midlifemonth.com 🧭 Listener Question Joanne ends this rant with a question for her audience: Should she create a dedicated program for people using weight loss medications (GLP-1s, etc.)—a short 3–4 hour video course called RX Success—to fill the massive coaching gap that doctors aren’t covering? Email Jo your thoughts at jo@theshrinkshop.com. ✅ Bottom line: Don’t buy into outdated “light weights and 45g ...
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    20 分
  • Fat Burning, Muscle Protection & Midlife Energy: SLU-PP-332 and 5-Amino-1MQ Explained

    Fat Burning, Muscle Protection & Midlife Energy: SLU-PP-332 and 5-Amino-1MQ Explained
    2025/08/27
    Midlife Mayhem – August 27, 2025

    SLU-PP-332, 5-Amino-1MQ, and the Truth About Midlife Muscle & Fat

    Hey friends, welcome back to Midlife Mayhem! I’ve just returned from a whirlwind trip through England and Greece—a mix of family remembrance, laughter, tears, chaos, and joy. I’m running on jet lag fumes, but I wanted to sit down and share something important with you today: two breakthrough compounds that could be absolute game-changers for midlife body composition—SLU-PP-332 and 5-Amino-1MQ.

    👉 SLU-PP-332 is now available at www.slu332.com 👉 5-Amino-1MQ is available at www.5amino.com 👉 You can also buy both together at a discounted bundle price on either site.

    And don’t forget—my Mastering Midlife program kicks off September 21 – November 1. Learn more and sign up at www.slu332.com

    • 5-Amino-1MQ → www.5amino.com

    • Mastering Midlife (Sept 21 – Nov 1) → www.midlifemonth.com

    • Email me anytime with questions: jo@theshrinkshop.com
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    41 分
  • The Liver–Body Composition Connection: Why Your Results May Be Stuck

    The Liver–Body Composition Connection: Why Your Results May Be Stuck
    2025/08/18

    We tend to think of the liver as “the detox organ.” We imagine green juice cleanses, detox teas, and vague ideas about “flushing toxins.” But your liver is so much more than that — it’s a powerhouse that affects every aspect of your body composition, from how much fat you store to how much energy you have.

    And while the liver is incredibly resilient (it can literally regrow after being partially removed), modern lifestyles are pushing it past its limits. That’s why we’re now seeing non-alcoholic fatty liver disease (NAFLD) not just in adults, but alarmingly, in children.

    In this episode, we’re diving deep into:

    1. The Liver’s Role in Fat Storage and Fat Burning

    • The liver makes fat — it’s not meant to store it. Excess sugar in your diet is converted in the liver into triglycerides (fat) and released into your bloodstream, where it eventually gets stored on your body.

    • When the liver is overwhelmed and can’t push fat out fast enough, it starts storing it internally — that’s how fatty liver develops.

    2. Your Liver as Your Energy Bank

    • About 75% of stored carbs (glycogen) live in your muscles — but muscle glycogen is locked away for personal use. Your biceps can’t “share” their carbs with the rest of your body.

    • The liver’s glycogen, however, can be broken down into glucose and released into your blood to keep your energy steady between meals, during sleep, or under stress.

    • If your blood sugar stays high even when you’ve cut carbs, your liver may be releasing stored glucose — often a sign of insulin resistance.

    3. The Liver’s Impact on Hormones

    • Cortisol clearance: The liver inactivates cortisol, helping prevent the muscle loss, midsection fat gain, water retention, collagen breakdown, and cravings that come with high cortisol.

    • Thyroid activation: The liver converts inactive T4 thyroid hormone into active T3 — your metabolism’s “go” signal. Poor liver function can mean slower metabolism and stubborn fat.

    4. How Modern Lifestyles Damage the Liver

    • Insulin resistance: A high-carb, low-activity lifestyle keeps insulin elevated. Overexposure makes the liver resistant to insulin’s signal, tricking it into thinking blood sugar is low — so it makes more sugar through gluconeogenesis, adding to the problem.

    • Leaky gut: Low-fiber, high-sugar, ultra-processed diets damage the gut lining. Toxins and undigested food particles leak into the bloodstream, triggering constant inflammation. That inflammation travels to — and damages — liver cells.

    • Poor food quality: You can’t out-supplement or out-macro a bad diet. “Weekend junk” and overly restrictive eating both take their toll on gut and liver health.

    5. Why This Matters for Body Composition

    A healthy liver helps you:

    • Efficiently use stored energy between meals (no energy crashes)

    • Convert thyroid hormones for optimal metabolism

    • Clear cortisol so you preserve muscle and control fat storage

    • Avoid fat buildup in the liver, which is linked to systemic inflammation and metabolic slowdown

    When the liver is struggling, everything from fat loss to hormone balance to workout recovery becomes harder.

    Key Takeaway

    The liver is a workhorse — but it’s underappreciated and often abused. If your fat loss has stalled, your energy is inconsistent, or your hormones are out of balance, your liver might be the missing link.

    📅 Next Live Program – Mastering Midlife (Sept 14 – Oct 25) If you’re ready to reset your metabolism, balance your hormones, and build a lean, strong body in midlife, join me for my ever-popular Mastering Midlife program.

    This year’s live program includes:

    • 11 live coaching calls over 5 weeks (with a built-in review week so you can catch up)

    • Meal plans, workouts, and supplement guidance

    • Deep dives into the 6 hormones that change with age

    • Sessions on exercise adjustments, nutrition upgrades, HRT/TRT, peptides, biohacks, and more

    • Men and women welcome — and the results are incredible

    We only run this once a year live. Reserve your spot today at: 👉 www.midlifemonth.com
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    19 分
  • Gene Editing: The New GMO Loophole You’re Not Hearing About

    Gene Editing: The New GMO Loophole You’re Not Hearing About
    2025/08/10

    We’ve all heard the term GMO — genetically modified organisms — and most of us know it’s controversial. But there’s a newer, slicker technology making its way into our food supply that’s flying under the radar: gene editing. It’s marketed as “natural,” it’s not always labeled, and it’s already on supermarket shelves. The problem? Most consumers have no idea it’s there… or what it could mean for our health.

    In this episode, I pull back the curtain on:

    • What gene editing actually is — how it differs from GMO technology, and why industry insiders argue it shouldn’t require labeling.

    • The rapid takeover of GMO crops in the U.S., from their quiet introduction to dominating over 90% of certain harvests in less than a decade.

    • Why Europe bans or strictly controls GMOs under the “precautionary principle” — and why the U.S. does the opposite, requiring proof of harm rather than proof of safety.

    • The glyphosate connection — and the staggering increases in allowable residues on soy, corn, wheat, and even animal feed (including a 2,000-fold increase on alfalfa).

    • How altered protein patterns in gene-edited plants and animals could confuse the immune system, potentially leading to chronic inflammation, autoimmune issues, and other long-term health risks.

    • Examples already in circulation: non-browning mushrooms, disease-resistant bananas, slick-coated cattle, faster-growing salmon, and more.

    • The labeling loophole: why most gene-edited products don’t have to be labeled in the U.S., and how companies use terms like “bioengineered” or QR codes instead of clear wording.

    • The eerie historical parallels with cigarettes and opioids — early warning signs ignored, public assurances of safety, and decades before the truth came out.

    I also share practical, actionable steps you can take now to reduce your exposure, including how to identify higher-risk foods, what to look for on labels, and why “100% organic” is a very different standard from “organic.”

    This isn’t fearmongering — it’s about being informed and proactive before the “monster” grows too big to contain.

    📅 Don’t Miss My Next Live Coaching Program – Mastering Midlife

    If you want to reclaim your energy, optimize your hormones, and build a lean, strong body in midlife and beyond, now is the time to join the ever-popular Mastering Midlife program.

    Live from September 14 – October 25, 2025, this year’s program is bigger and better than ever, with a brand-new pacing designed for busy lives:

    • 11 live coaching calls over five weeks (3 weeks on, 1 week off to catch up, then 2 final weeks)

    • Expert-led sessions on the six hormones that shift in midlife, how to adapt your training, how to fine-tune your nutrition, plus deep dives into HRT, TRT, peptides, biohacks, skin and muscle health, and more

    • Structured meal plans, targeted workouts, and supplement guidance included

    • The chance to connect with a motivated, like-minded community — men and women welcome

    • Only runs once per year in the live format — payment plan available

    Reserve your spot at www.midlifemonth.com and step into the healthiest, strongest version of yourself.
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    30 分
  • Starbucks Stomach

    Starbucks Stomach
    2025/07/31

    If you’ve ever left Starbucks feeling bloated, sluggish, or… ahem… blocked up for days, you’re not imagining things. In this episode, I dive deep into why Starbucks hits your gut differently than your local coffee shop. From dark roasted beans and ultra-pasteurized milk to highly processed plant-based alternatives and the whole A1 vs A2 milk debate, I break down exactly what’s going on — and why it matters for your digestion, energy, and even your waistline.

    I also explain why even if you don’t think you’re lactose intolerant, you might still react to certain dairy proteins — and how a simple milk swap could make a world of difference.

    This topic comes straight out of my Tight28 program’s dairy module, so if you’ve been struggling with gut discomfort, unexplained puffiness, or sluggish digestion, you’ll definitely want to listen in.

    What You’ll Learn in This Episode

    ☕ The Coffee Factor

    • Why Starbucks uses very dark roasted beans — and how this affects bitterness, bile release, and gut motility.

    • How ultra-high volume roasting and older beans can increase oxidized oils — and why oxidized oils = gut irritation.

    • Why your local café’s medium roast and fresher beans are usually gentler on digestion.

    🥛 The Dairy Factor

    • The difference between regular pasteurization and ultra-pasteurization — and how extreme heat denatures milk proteins like casein.

    • Why casein (especially A1 beta-casein) is already hard to digest — and how ultra-pasteurization makes it worse.

    • Why large latte servings = large dairy hits that can trigger bloating and constipation.

    🌱 The Milk Alternative Trap

    • Why Starbucks oat, almond, and soy milks are highly processed and full of gums and emulsifiers.

    • How gums/emulsifiers can damage gut lining, worsen leaky gut, and trigger bloating or sluggish digestion.

    • Why oat milk’s beta-glucans and residual enzymes can ferment in the gut and cause discomfort.

    🐄 A1 vs A2 Milk Explained

    • A1 milk (common in U.S. dairy from Holstein cows) contains a beta-casein variant that releases BCM-7 during digestion.

    • BCM-7 slows gut motility, irritates the gut lining, and can trigger histamine release → bloating, puffiness, water retention.

    • A2 milk (from Jersey/Guernsey cows, goats, sheep, buffalo) produces minimal BCM-7 — often eliminating symptoms entirely.

    • Why switching to A2 can be a game-changer for digestion, even if you’re not lactose intolerant.

    Key Takeaways

    • Starbucks’ combination of dark roast bitterness, ultra-pasteurized A1 milk, and/or processed plant milks can be a “perfect storm” for gut issues.

    • If you want to keep enjoying coffee without the digestive misery:

      • Switch to medium roast, freshly ground beans.

      • Use A2 dairy or goat/sheep/buffalo milk.

      • Skip processed plant milks with gums/emulsifiers.

      • Try smaller coffee sizes or Americano-style drinks instead of milk-heavy lattes.

    • Gut irritation isn’t just about discomfort — it can contribute to systemic inflammation, histamine buildup, and even changes in body composition.

    Want to Go Deeper?

    This episode barely scratches the surface of what I teach in Tight28, my 28-day program designed to uncover hidden food sensitivities, calm inflammation, and get your digestion — and your body composition — working in your favor.

    Check it out here: www.jlcstrong.com

    Resources & Links Mentioned

    • 5-Amino-1MQ: www.5amino.com

    • My upcoming SLU-PP-332 release — stay tuned!

    • Email me anytime with questions: jo@theshrinkshop.com

    If you enjoyed this episode, please subscribe, leave a review, and share it with someone who’s still wondering why their Starbucks habit might be causing their gut drama.
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    22 分
  • Are You Building Muscle or Breaking Down? Let Bloodwork Decide

    Are You Building Muscle or Breaking Down? Let Bloodwork Decide
    2025/07/29

    If you’ve hit a plateau with your workouts… if you're gaining fat despite training hard… or if you're feeling constantly tired and inflamed, your bloodwork might have the answers.

    In this episode, we dive into:

    • What the DHEA-to-cortisol ratio really tells you about stress, recovery, and resilience

    • The exact numbers you want to see (with examples)

    • Key blood markers like CK, AST, LDH, CRP, and what they reveal about muscle breakdown

    • How to interpret patterns that signal overtraining or burnout

    Because you don’t build muscle in the gym—you build it when you're recovering properly. Let's make sure you're set up to build, not break down.

    🔬 DHEA-to-Cortisol Ratio: What It Means Hormone Ratio What It Means ✅ ≥ 10:1 Healthy recovery, strong stress resilience, good environment for fat loss & muscle gain ⚠️ ≤ 5:1 Stress outweighs recovery; may stall progress, impair sleep, increase fat storage ❌ ≤ 2:1 Burnout, poor training response, HPA axis dysfunction, inflammation, fatigue 🧮 Example Calculations:

    • DHEA-S 150 / Cortisol 10 = 15:1 ✅

    • DHEA-S 90 / Cortisol 18 = 5:1 ⚠️

    • DHEA-S 40 / Cortisol 22 = 1.8:1 ❌

    💪 Blood Markers That Reveal Muscle Breakdown Marker Optimal Range Concern Threshold What It Indicates DHEA-S W: 100–200 / M: 150–300 mcg/dL <70 (W), <100 (M) Anabolic status / stress buffer Cortisol (AM) 8–15 mcg/dL >23 (stress), <6 (burnout) Stress response or adrenal fatigue Creatine Kinase (CK) 30–150 U/L >500 = intense training, >1,000 = concern Muscle breakdown marker AST / ALT AST <40 / ALT <56 U/L AST >80 without liver issue = muscle strain Post-exercise stress or liver burden LDH 140–280 U/L >400 U/L Chronic tissue stress or poor recovery CRP (hs-CRP) <1.0 mg/L >3.0 = systemic inflammation Inflammation, potential overtraining Urea / Creatinine Urea: 10–20 / Cr: <1.2 Depends on hydration, protein, renal function Contextual clues for stress and protein turnover 🧠 What Affects These Markers?

    • Overtraining or lack of deloads

    • Low-carb or low-calorie diets

    • Emotional stress and poor sleep

    • Hormonal changes (especially in midlife)

    • Poor gut health or chronic inflammation

    These markers give you insight into whether your training is building your body—or breaking it down.

    🧬 New Peptides + Supplements

    💊 Now Available: 5-Amino-1MQ A powerful compound that supports fat loss, muscle preservation, and energy through NAD+ pathways.

    🧪 Coming Late August: SLU-PP-332 If you'd like to be notified the moment it's available, email me at 👉 www.jlcstrong.com Let’s find the right fit for your body and your goals.
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    29 分